BRD7 information

BRD7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2I7K
Identifiers
Aliases	BRD7, BP75, CELTIX1, NAG4, bromodomain containing 7, SMARCI1
External IDs	OMIM: 618489; MGI: 1349766; HomoloGene: 8085; GeneCards: BRD7; OMA:BRD7 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	50,368,988 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	88,362,194 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; ventricular zone; ; ganglionic eminence; ; islet of Langerhans; ; gonad; ; Achilles tendon; ; C1 segment; ; right testis; ; testicle; ; popliteal artery;
	Top expressed in
	genital tubercle; ; tail of embryo; ; ventricular zone; ; zygote; ; cardiac muscle tissue of left ventricle; ; interventricular septum; ; muscle of thigh; ; secondary oocyte; ; lens; ; condyle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; histone binding; p53 binding; transcription factor binding; protein binding; transcription corepressor activity; lysine-acetylated histone binding;
Cellular component	nucleus; nucleoplasm; cytoplasm; cytosol;
Biological process	regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; negative regulation of G1/S transition of mitotic cell cycle; cell cycle; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; Wnt signaling pathway; transcription, DNA-templated; negative regulation of cell population proliferation; positive regulation of histone acetylation; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	29117
	26992
	ENSG00000166164
	ENSMUSG00000031660
	Q9NPI1
	O88665
	NM_001173984; NM_013263
	NM_012047
	NP_001167455; NP_037395
NP_036177; NP_001363942; NP_001363943; NP_001363944; NP_001363945;
	NP_001363946
	Wikidata
View/Edit Human	View/Edit Mouse

Bromodomain-containing protein 7 is a protein that in humans is encoded by the BRD7 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166164 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031660 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cuppen E, van Ham M, Pepers B, Wieringa B, Hendriks W (November 1999). "Identification and molecular characterization of BP75, a novel bromodomain-containing protein". FEBS Lett. 459 (3): 291–298. doi:10.1016/S0014-5793(99)01191-6. PMID 10526152. S2CID 41216030.
^ Kaeser MD, Aslanian A, Dong MQ, Yates JR III, Emerson BM (November 2008). "BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells". J Biol Chem. 283 (47): 32254–32263. doi:10.1074/jbc.M806061200. PMC 2583284. PMID 18809673.
^ "Entrez Gene: BRD7 bromodomain containing 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166164 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031660 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10526152-5] Cuppen E, van Ham M, Pepers B, Wieringa B, Hendriks W (November 1999). "Identification and molecular characterization of BP75, a novel bromodomain-containing protein". FEBS Lett. 459 (3): 291–298. doi:10.1016/S0014-5793(99)01191-6. PMID 10526152. S2CID 41216030.

[pmid18809673-6] Kaeser MD, Aslanian A, Dong MQ, Yates JR III, Emerson BM (November 2008). "BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells". J Biol Chem. 283 (47): 32254–32263. doi:10.1074/jbc.M806061200. PMC 2583284. PMID 18809673.

[entrez-7] "Entrez Gene: BRD7 bromodomain containing 7".

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