HNRPUL1 information

HNRNPUL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZRJ
Identifiers
Aliases	HNRNPUL1, E1B-AP5, E1BAP5, HNRPUL1, heterogeneous nuclear ribonucleoprotein U like 1
External IDs	OMIM: 605800; MGI: 2443517; HomoloGene: 31419; GeneCards: HNRNPUL1; OMA:HNRNPUL1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	41,307,787 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	25,454,182 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; sural nerve; ; gastric mucosa; ; left ovary; ; stromal cell of endometrium; ; right ovary; ; bone marrow cells; ; body of uterus; ; popliteal artery;
	Top expressed in
	internal carotid artery; ; Gonadal ridge; ; external carotid artery; ; genital tubercle; ; molar; ; mesenteric lymph nodes; ; Rostral migratory stream; ; tail of embryo; ; conjunctival fornix; ; ventricular zone;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	enzyme binding; protein binding; RNA binding;
Cellular component	nucleus; nucleoplasm;
Biological process	mRNA splicing, via spliceosome; response to virus; RNA processing; regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	11100
	232989
	ENSG00000105323
	ENSMUSG00000040725
	Q9BUJ2
	Q8VDM6
NM_001301016; NM_007040; NM_144732; NM_144733; NM_144734;
	NM_001321208; NM_001321211
	NM_144922; NM_178089; NM_001360789
	NP_001287945; NP_001308137; NP_001308140; NP_008971; NP_653333
	NP_659171; NP_835190; NP_001347718
	Wikidata
View/Edit Human	View/Edit Mouse

Heterogeneous nuclear ribonucleoprotein U-like protein 1 is a protein that in humans is encoded by the HNRNPUL1 gene.^[5]^[6]^[7]

This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. HNRPUL1 also participates in ATR protein kinase signalling pathways during adenovirus infection. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105323 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040725 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gabler S, Schutt H, Groitl P, Wolf H, Shenk T, Dobner T (Oct 1998). "E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs". J Virol. 72 (10): 7960–71. doi:10.1128/JVI.72.10.7960-7971.1998. PMC 110131. PMID 9733834.
^ Kzhyshkowska J, Rusch A, Wolf H, Dobner T (Apr 2003). "Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7". Biochem J. 371 (Pt 2): 385–93. doi:10.1042/BJ20021281. PMC 1223277. PMID 12489984.
^ ^a ^b "Entrez Gene: HNRPUL1 heterogeneous nuclear ribonucleoprotein U-like 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105323 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040725 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9733834-5] Gabler S, Schutt H, Groitl P, Wolf H, Shenk T, Dobner T (Oct 1998). "E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs". J Virol. 72 (10): 7960–71. doi:10.1128/JVI.72.10.7960-7971.1998. PMC 110131. PMID 9733834.

[pmid12489984-6] Kzhyshkowska J, Rusch A, Wolf H, Dobner T (Apr 2003). "Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7". Biochem J. 371 (Pt 2): 385–93. doi:10.1042/BJ20021281. PMC 1223277. PMID 12489984.

[entrez-7] "Entrez Gene: HNRPUL1 heterogeneous nuclear ribonucleoprotein U-like 1".

HNRPUL1 information

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PRMT2

BRD7