Aurora kinase C information

AURKC
Identifiers
Aliases	AURKC, AIE2, AIK3, ARK3, AurC, SPGF5, STK13, aurora-C, HEL-S-90, aurora kinase C
External IDs	OMIM: 603495; MGI: 1321119; HomoloGene: 68302; GeneCards: AURKC; OMA:AURKC - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	57,235,548 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	7,006,090 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; left testis; ; right testis; ; gonad; ; testicle; ; sperm; ; stromal cell of endometrium; ; spleen; ; apex of heart;
	Top expressed in
	secondary oocyte; ; zygote; ; primary oocyte; ; morula; ; blastocyst; ; male human body; ; male reproductive system; ; testicle; ; embryo; ; spermatocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; histone serine kinase activity; kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; ATP binding; protein binding;
Cellular component	cytoplasm; spindle; spindle pole centrosome; chromosome; chromosome passenger complex; midbody; spindle microtubule; spindle midzone; chromosome, centromeric region; cytoskeleton; condensed chromosome; nucleus;
Biological process	phosphorylation; mitotic spindle midzone assembly; histone modification; oocyte development; positive regulation of cytokinesis; cell division; protein phosphorylation; meiosis; spindle midzone assembly; spermatogenesis; cell cycle; attachment of spindle microtubules to kinetochore; cytokinesis; mitotic spindle organization; regulation of cytokinesis;
	Sources:Amigo / QuickGO
Orthologs
	6795
	20871
	ENSG00000105146
	ENSMUSG00000070837
	Q9UQB9
	O88445
	NM_001015878; NM_001015879; NM_003160
	NM_001080965; NM_001080966; NM_020572
	NP_001015878; NP_001015879; NP_003151
	NP_001074434; NP_001074435; NP_065597
	Wikidata
View/Edit Human	View/Edit Mouse

Aurora kinase C, also Serine/threonine-protein kinase 13 is an enzyme that in humans is encoded by the AURKC gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105146 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070837 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bernard M, Sanseau P, Henry C, Couturier A, Prigent C (November 1998). "Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast Ipl1 that maps on chromosome 19q13.3-ter". Genomics. 53 (3): 406–9. doi:10.1006/geno.1998.5522. PMID 9799611.
^ "Entrez Gene: AURKC aurora kinase C".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105146 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000070837 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9799611-5] Bernard M, Sanseau P, Henry C, Couturier A, Prigent C (November 1998). "Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast Ipl1 that maps on chromosome 19q13.3-ter". Genomics. 53 (3): 406–9. doi:10.1006/geno.1998.5522. PMID 9799611.

[entrez-6] "Entrez Gene: AURKC aurora kinase C".

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