In genetics, association mapping, also known as "linkage disequilibrium mapping", is a method of mapping quantitative trait loci (QTLs) that takes advantage of historic linkage disequilibrium to link phenotypes (observable characteristics) to genotypes (the genetic constitution of organisms), uncovering genetic associations.[1][2]
^Breseghello, Flavio; Sorrells, Mark E (2006-02-01). "Association Mapping of Kernel Size and Milling Quality in Wheat ( Triticum aestivum L.) Cultivars". Genetics. 172 (2): 1165–1177. doi:10.1534/genetics.105.044586. ISSN 1943-2631. PMC 1456215. PMID 16079235.
^Zondervan, Krina T.; Cardon, Lon R. (2007-02-01). "Designing candidate gene and genome-wide case–control association studies". Nature Protocols. 2 (10): 2492–2501. doi:10.1038/nprot.2007.366. ISSN 1750-2799. PMC 4180089. PMID 17947991.
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simultaneously in multiple individuals Associationmapping Genetic association Genetic linkage Genome-wide association study Identity by type Linkage disequilibrium...
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method suffers somewhat from the essentially global nature of the associationmapping, as well as from developers' incomplete avoidance of extensions when...