Molecular breeding is the application of molecular biology tools, often in plant breeding[1][2] and animal breeding.[3][4] In the broad sense, molecular breeding can be defined as the use of genetic manipulation performed at the level of DNA to improve traits of interest in plants and animals, and it may also include genetic engineering or gene manipulation, molecular marker-assisted selection, and genomic selection.[5] More often, however, molecular breeding implies molecular marker-assisted breeding (MAB) and is defined as the application of molecular biotechnologies, specifically molecular markers, in combination with linkage maps and genomics, to alter and improve plant or animal traits on the basis of genotypic assays.[6]
The areas of molecular breeding include:
QTL mapping or gene discovery
Marker assisted selection and genomic selection[7][8][9]
Genetic engineering
Genetic transformation
^Voosen, P. (2009). "Molecular Breeding Makes Crops Hardier and More Nutritious Markers, knockouts and other technical advances improve breeding without modifying genes". Scientific American.
^"Stephen P. Moose* and Rita H. Mumm (2008) Molecular Plant Breeding as the Foundation for 21st Century Crop Improvement, Plant Physiology 147:969-977".
^Dekkers, Jack C. M.; Hospital, Frédéric (2002). "The use of molecular genetics in the improvement of agricultural populations". Nature Reviews Genetics. 3 (1): 22–32. doi:10.1038/nrg701. PMID 11823788. S2CID 32216266.
^C.M. Dekkers, Jack (2012). "Application of Genomics Tools to Animal Breeding". Current Genomics. 13 (3): 207–212. doi:10.2174/138920212800543057. PMC 3382275. PMID 23115522.
^Ribaut, J-M; de Vicente, Mc; Delannay, X (April 2010). "Molecular breeding in developing countries: challenges and perspectives". Current Opinion in Plant Biology. 13 (2): 213–218. doi:10.1016/j.pbi.2009.12.011. PMID 20106715.
^Hollington, P.A.; Steele, Katherine A. (2007), "Participatory Breeding For Drought and Salt Tolerant Crops", Advances in Molecular Breeding Toward Drought and Salt Tolerant Crops, Dordrecht: Springer Netherlands, pp. 455–478, doi:10.1007/978-1-4020-5578-2_18, ISBN 978-1-4020-5577-5, retrieved 2020-10-02
^Meuwissen, T. H. E.; Hayes, B. J.; Goddard, M. E. (2001-04-01). "Prediction of Total Genetic Value Using Genome-Wide Dense Marker Maps". Genetics. 157 (4): 1819–1829. doi:10.1093/genetics/157.4.1819. ISSN 0016-6731. PMC 1461589. PMID 11290733.
^Jannink, Jean-Luc; Lorenz, Aaron J.; Iwata, Hiroyoshi (2010-03-01). "Genomic selection in plant breeding: from theory to practice". Briefings in Functional Genomics. 9 (2): 166–177. doi:10.1093/bfgp/elq001. ISSN 2041-2649. PMID 20156985.
production through plant breeding. Modern plant breeding is applied genetics, but its scientific basis is broader, covering molecular biology, cytology, systematics...
SNP markers have turned out to be a potential tool in breeding programs in several crops. Molecular mapping aids in identifying the location of particular...
growers have employed many breeding techniques, starting with traditional plant breeding and then moving on to molecularbreeding and genetic engineering...
DNA shuffling, also known as molecularbreeding, is an in vitro random recombination method to generate mutant genes for directed evolution and to enable...
costly (both directly and for the equipment), and inflexible. Other molecularbreeding tools have produced rice blast resistant cultivars. DNA microarray...
Selective breeding (also called artificial selection) is the process by which humans use animal breeding and plant breeding to selectively develop particular...
conditions.[citation needed] A useful molecular marker known as a simple sequence repeat (SSR) is used in breeding with respect to selection. SSRs are segments...
scientific theory of animal breeding incorporates population genetics, quantitative genetics, statistics, and recently molecular genetics and is based on...
atlas is available from Shakoor et al., 2014 with 27,577 genes. For molecularbreeding (or other purposes) an SNP array has been created by Bekele et al...
August 2015). Current Technologies in Plant MolecularBreeding: A Guide Book of Plant MolecularBreeding for Researchers. Springer. p. 242. ISBN 978-94-017-9996-6...
Zbigniew (2019-03-13). "Genetic and molecular bases of cucumber (Cucumis sativus L.) sex determination". MolecularBreeding. 39 (3): 50. doi:10.1007/s11032-019-0959-6...
"Phytate: impact on environment and human nutrition. A challenge for molecularbreeding". Journal of Zhejiang University Science B. 9 (3): 165–91. doi:10...
science of genetics. Modern plant breeding is applied genetics, but its scientific basis is broader, covering molecular biology, cytology, systematics,...
Hiwasa-Tanase K, Takane K, Ezura H, Mizoguchi T (September 2010). "Molecularbreeding of tomato lines for mass production of miraculin in a plant factory"...
Molecular Weight (LMW) Glutenin Composition of Transgenic Durum Wheat: Effects on Glutenin Polymer Size and Gluten Functionality". MolecularBreeding...
array to a more economical 35k for genomic selection in the program. Molecularbreeding has improved greatly in the few years up to 2020[update] and the rapid...
Kole, C. (ed.). Pulses, Sugar and Tuber Crops, Genome Mapping and MolecularBreeding in Plants. Vol. 3. Berlin, Heidelberg: Springer-Verlag. pp. 49–67...
genome is of great value to DArT and has large implications in the molecularbreeding sector. By comparing crops with phenotypes such as higher yields of...
"Carrot". In Cole, Chittaranjan (ed.). Vegetables. Genome Mapping and MolecularBreeding in Plants. Vol. 5. New York, NY: Springer. pp. 162–184. ISBN 978-3-540-34535-0...
Captive breeding, also known as captive propagation, is the process of keeping plants or animals in controlled environments, such as wildlife reserves...
) R. Br., using a genotyping-by-sequencing (GBS) approach" (PDF). MolecularBreeding. 35 (1). doi:10.1007/s11032-015-0212-x. ISSN 1380-3743. National Key...
(2015-08-26). Current Technologies in Plant MolecularBreeding: A Guide Book of Plant MolecularBreeding for Researchers. Springer. p. 242. ISBN 9789401799966...
"Phytate: Impact on environment and human nutrition. A challenge for molecularbreeding". Journal of Zhejiang University. Science. B. 9 (3): 165–191. doi:10...
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