Artemether is a medication used for the treatment of malaria.[1][2] The injectable form is specifically used for severe malaria rather than quinine.[2] In adults, it may not be as effective as artesunate.[2] It is given by injection in a muscle.[2] It is also available by mouth in combination with lumefantrine, known as artemether/lumefantrine.[1][3]
Artemether causes relatively few side effects.[4] An irregular heartbeat may rarely occur.[4] While there is evidence that use during pregnancy may be harmful in animals, there is no evidence of concern in humans.[4] The World Health Organization (WHO) therefore recommends its use during pregnancy.[4] It is in the artemisinin class of medication.[4]
Artemether has been studied since at least 1981, and has been in medical use since 1987.[5] It is on the World Health Organization's List of Essential Medicines.[6]
^ abc"Artemether and Lumefantrine (Monograph)". Drugs.com. 22 February 2023. Retrieved 17 February 2024.
^ abcdeEsu EB, Effa EE, Opie ON, Meremikwu MM (June 2019). "Artemether for severe malaria". The Cochrane Database of Systematic Reviews. 6 (6): CD010678. doi:10.1002/14651858.CD010678.pub3. PMC 6580442. PMID 31210357.
^Cite error: The named reference Coartem FDA label was invoked but never defined (see the help page).
^ abcdeKovacs SD, Rijken MJ, Stergachis A (February 2015). "Treating severe malaria in pregnancy: a review of the evidence". Drug Safety. 38 (2): 165–181. doi:10.1007/s40264-014-0261-9. PMC 4328128. PMID 25556421.
^Rao Y, Zhang D, Li R (2016). Tu Youyou and the Discovery of Artemisinin: 2015 Nobel Laureate in Physiology or Medicine. World Scientific. p. 162. ISBN 9789813109919. Archived from the original on 2017-09-10.
^World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 2019. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
Artemether is a medication used for the treatment of malaria. The injectable form is specifically used for severe malaria rather than quinine. In adults...
artemether. The term "co-artemether" is sometimes used to describe this combination. Lumefantrine has a much longer half-life compared to artemether,...
active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic...
combination therapy[verification needed] (e.g., using agents such as artemether and lumefantrine against chloroquine-resistant Plasmodium falciparum...
Retrieved 14 May 2020. Esu EB, Effa EE, Opie ON, Meremikwu MM (June 2019). "Artemether for severe malaria". The Cochrane Database of Systematic Reviews. 6 (6):...
resistance to any single drug component. Artemether-lumefantrine (six-dose regimen) is more effective than the artemether-lumefantrine (four-dose regimen) or...
treatment with any of five artemisinin-based combination therapies (ACTs): artemether/lumefantrine, artesunate/amodiaquine (ASAQ), artesunate/mefloquine,...
ether-based extraction method, further showing the artemisinin derivative artemether to be an effective antimalarial drug. Artemisinin is a sesquiterpene lactone...
For their high efficacy, safety and stability, artemisinins such as artemether and artesunate became the drugs of choice in treating falciparum malaria...
consistent across all trials. Artesunate's efficacy is comparable to that of artemether, another artemisinin derivative, in treating adults for severe malaria...
found that artemether prevents the development of adult worms, thus decreasing egg production in the host. If both praziquantel and artemether can be used...
annua. Zhou specifically worked on artemether, one of the derivatives of artemisinin. In 1985 he combined artemether with another drug lumefantrine into...
essential for its anti-malarial activity. Its derivatives, artesunate and artemether, have been used in clinics since 1987 for the treatment of drug-resistant...
Phase III trial of chlorproguanil-dapsone-artesunate (Dacart™) versus artemether-lumefantrine (Coartem®) and confirmation of findings in a comparative...
ergot,[citation needed] and the semisynthesis of the antimalarial drug artemether from naturally-occurring artemisinin.[non-primary source needed][non-primary...
fasciolosis, as it is highly effective against both mature and immature flukes. Artemether has been demonstrated in vitro to be equally effective. Though slightly...
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