Antithyroid autoantibodies (or simply antithyroid antibodies) are autoantibodies targeted against one or more components on the thyroid. The most clinically relevant anti-thyroid autoantibodies are anti-thyroid peroxidase antibodies (anti-TPO antibodies, TPOAb), thyrotropin receptor antibodies (TRAb) and thyroglobulin antibodies (TgAb). TRAb's are subdivided into activating, blocking and neutral antibodies, depending on their effect on the TSH receptor. Anti-sodium/iodide (Anti–Na+/I−) symporter antibodies are a more recent discovery and their clinical relevance is still unknown. Graves' disease and Hashimoto's thyroiditis are commonly associated with the presence of anti-thyroid autoantibodies. Although there is overlap, anti-TPO antibodies are most commonly associated with Hashimoto's thyroiditis and activating TRAb's are most commonly associated with Graves' disease. Thyroid microsomal antibodies were a group of anti-thyroid antibodies; they were renamed after the identification of their target antigen (TPO).[1][2][3][4]
^Saravanan P, Dayan CM (June 2001). "Thyroid autoantibodies". Endocrinology and Metabolism Clinics of North America. 30 (2): 315–37, viii. doi:10.1016/S0889-8529(05)70189-4. PMID 11444165.
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Antithyroidautoantibodies (or simply antithyroid antibodies) are autoantibodies targeted against one or more components on the thyroid. The most clinically...
Radioiodine uptake by the thyroid, thyroid scan, and measurement of antithyroidautoantibodies (thyroidal thyrotropin receptor antibodies are positive in Graves...
2007.0310. PMID 18631006. Nagasaka A, Hidaka H (Jul 1976). "Effect of antithyroid agents 6-propyl-2-thiouracil and 1-methyl-2-mercaptoimidazole on human...
Candeago RM, Cimini N, Conte F, Gentile M, et al. (February 2003). "Antithyroid antibodies in the CSF: their role in the pathogenesis of Hashimoto's...
long-term quality-of-life follow up of patients randomized to treatment with antithyroid drugs, radioiodine, or surgery". Thyroid. 15 (11): 1279–86. doi:10.1089/thy...
hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid gland. Thyroid surgery...
including drugs (non-steroidal anti-inflammatory drugs, antiepileptics, antithyroid, and antibiotics) and viral infection. Agranulocytosis has a mortality...
eosinophilia. High titers of autoantibodies are frequently observed, including rheumatoid factor, antinuclear antibody, and antithyroid antibodies. The fibrotic...
maternal flavonoid ingestion during pregnancy and to other environmental antithyroid agents". Journal of the Neurological Sciences (Review). 262 (1–2): 15–26...
thyroiditis is associated with thyroid peroxidase and thyroglobulin autoantibodies Hashitoxicosis Hypothyroidism Hyperthyroidism Hypoparathyroidism; can...
initially elevated but decreases with antithyroid treatment in parallel to declining TSH receptor autoantibody titres. Although takotsubo syndrome (TTS)...
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