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Antitermination information


Antitermination is the prokaryotic cell's aid to fix premature termination of RNA synthesis during the transcription of RNA. It occurs when the RNA polymerase ignores the termination signal and continues elongating its transcript until a second signal is reached. Antitermination provides a mechanism whereby one or more genes at the end of an operon can be switched either on or off, depending on the polymerase either recognizing or not recognizing the termination signal.

Antitermination is used by some phages to regulate progression from one stage of gene expression to the next. The lambda gene N, codes for an antitermination protein (pN) that is necessary to allow RNA polymerase to read through the terminators located at the ends of the immediate early genes. Another antitermination protein, pQ, is required later in phage infection. pN and pQ act on RNA polymerase as it passes specific sites. These sites are located at different relative positions in their respective transcription units.

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Antitermination

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Antitermination is the prokaryotic cell's aid to fix premature termination of RNA synthesis during the transcription of RNA. It occurs when the RNA polymerase...

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Lambda phage

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characterized lambdoid phages possess an N protein-mediated transcription antitermination mechanism, with the exception of phage HK022. The genome contains 48...

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Termination signal

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genes can be increased by inhibiting signal terminators, known as antitermination, which allows for transcription to continue beyond the termination...

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PyrG leader

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sequences of Bacillus subtilis pyrG mRNA essential for regulation by antitermination". J Bacteriol. 184 (23): 6734–6738. doi:10.1128/jb.184.23.6734-6738...

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Abortive initiation

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Nguyen HM, Kang C (2010). "Tiny abortive initiation transcripts exert antitermination activity on an RNA hairpin-dependent intrinsic terminator". Nucleic...

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Ranjan Sen

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on transcription antitermination mechanisms by PUT RNA. At CDFD, the team led by him is involved in the studies of antitermination in prokaryotes, combining...

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Bacterial transcription

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sequence until the next one is reached. This phenomenon is known as antitermination and is utilized by certain bacteriophages. "Prokaryotic Transcription...

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Intrinsic termination

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W. (1999). "Mechanism of Intrinsic Transcription Termination and Antitermination". Science. 284 (5414): 611–5. Bibcode:1999Sci...284..611Y. doi:10.1126/science...

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Transsulfuration pathway

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methionine biosynthesis in Bacillus subtilis is controlled by transcription antitermination". Microbiology. 148 (Pt 2): 507–518. doi:10.1099/00221287-148-2-507...

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CII protein

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translation of the cII gene within the early right transcript depends on N antitermination cII mRNA degradation: The mRNA coding for the C-terminal end of cII...

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RNA motif

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Henkin TM (August 1993). "tRNA as a positive regulator of transcription antitermination in B. subtilis". Cell. 74 (3): 475–82. doi:10.1016/0092-8674(93)80049-k...

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HutP

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A. Ito, Y. Kurusu, K. Taira, cis-acting regulatory sequences for antitermination in the transcript of the Bacillus subtilis hut operon and histidine-dependent...

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Termination factor

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process of termination by Rho factor is regulated by attenuation and antitermination mechanisms, competing with elongation factors for overlapping utilization...

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