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Chemical compound
Anisomycin, also known as flagecidin, is an antibiotic produced by Streptomyces griseolus which inhibits eukaryotic protein synthesis. Partial inhibition of DNA synthesis occurs at anisomycin concentrations that effect 95% inhibition of protein synthesis.[2] Anisomycin can activate stress-activated protein kinases, MAP kinase and other signal transduction pathways.
^Anisomycin Archived January 19, 2012, at the Wayback Machine from Sigma Aldrich
^Grollman, Arthur P. (1967). "Inhibitors of protein biosynthesis. II. Mode of action of anisomycin". The Journal of Biological Chemistry. 242 (13): 3226–33. doi:10.1016/S0021-9258(18)95953-3. PMID 6027796.
Anisomycin, also known as flagecidin, is an antibiotic produced by Streptomyces griseolus which inhibits eukaryotic protein synthesis. Partial inhibition...
showed that anisomycin can sensitize metastatic epithelial cells to anoikis and reduce circulating tumor cell implantation in vivo. Anisomycin achieved this...
amygdala has been shown to prevent long-term memory for fear conditioning. Anisomycin inhibits the production of proteins. In tests where it is delivered to...
injected with anisomycin, an antibiotic that restricts protein synthesis, at different points in time. The rats that were injected with anisomycin after consolidation...
adapted for research purposes. In research, commonly used PSI's include anisomycin, cycloheximide, and puromycin - although the use of puromycin has stopped...
oligomycins (oligomycin A, oligomycin B, oligomycin C) and the antibiotics anisomycin and sinefungin. Tohyama, Shigehiro; Kakinuma, Katsumi; Eguchi, Tadashi...
and JNK activation are not required for cell death induced by anisomycin and anisomycin analogues". Biochemical and Biophysical Research Communications...
specifically fungi that are susceptible to "fungicidal substances of the anisomycin group".[citation needed] This bacterium can also be used to determine...
where he published a paper with John P. Schaefer on the structure of anisomycin. Wheatley’s last position was in the Department of Physical Chemistry...
C14H19NO4 (molar mass: 265.31 g/mol, exact mass: 265.1314 u) may refer to: Anisomycin, also known as flagecidin Filenadol This set index page lists chemical...
retention of olfactory memories in honeybees is impaired by actinomycin D and anisomycin". The European Journal of Neuroscience. 10 (8): 2742–5. doi:10.1046/j...
synthesis within the particular dendritic spine, as proven by injecting anisomycin into a dendritic spine and observing the resulting absence of late LTP...
post-retrieval an intra-amygdalar infusion of a known amnesic agent, anisomycin, rats failed to recall a rapidly learned fear memory. Hippocampal lesions...
acetate, propionate, and citrate. Sensitivity to novobiocin, bacitracin, anisomycin, aphidicolin, and rifampicin have been observed. However, no sensitivity...
the cytokine TGFβ, the death effector TRAIL or chemical drugs such as anisomycin. PUMA protein is degraded in a proteasome dependent manner and its degradation...
PMID 15684425. Wang X, Mader MM, Toth JE, et al. (2005). "Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an...
antibiotics, including Vancomycin and Tetracycline, but can be killed by Anisomycin. This organism does not produce the enzymes gelatinase or amylase, so...
response to interleukin-1 cellular response to sorbitol cellular response to anisomycin cellular response to sodium arsenite MAPK cascade intracellular signal...
(2000). "The net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock". Mol. Cell. Biol. 19 (10): 7076–87. doi:10.1128/mcb...
various stress conditions such as UV irradiation, oxidative stress, and anisomycin treatment or JDP2 is also regulated by other kinases such as p38 MAPK...
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