Ancylostoma caninum is a species of nematode known as a hookworm, which principally infects the small intestine of dogs.[1][2][3] The result of A. caninum infection ranges from asymptomatic cases to death of the dog; better nourishment, increasing age, prior A. caninum exposure, or vaccination are all linked to improved survival.[2][4][5][6] Other hosts include carnivores such as wolves, foxes, and cats, with a small number of cases having been reported in humans.[1][2]
Warm and moist conditions are important to allow survival of A. caninum during the free-living stages of its lifecycle, so it is largely restricted to temperate, tropical, and subtropical regions.[3][7] In parts of the world where these climatic requirements are met such as Sri Lanka, Southeast Asia, and Malaysia, A. caninum is the main cause of hookworm disease in canines.[5][7]
^ abSaeed S (2003). "Ancylostoma caninum". Animal Diversity Web. Retrieved March 20, 2013.
^ abcMarquardt W, Demaree, Grieve (2000). Parasitology and Vector Biology (2nd ed.). Harcourt Academic. pp. 370–376. ISBN 978-0121707552.
^ abOlsen W (1986). Animal Parasites: their lifecycles and ecology (3rd ed.). Dover. pp. 399–416. ISBN 978-0486651262.
^Miller (1965). "Influence of Age and Sex on Susceptibility of Dogs to Primary Infection with Ancylostoma caninum". The Journal of Parasitology. 51 (5): 701–704. doi:10.2307/3276142. JSTOR 3276142. PMID 5857264.
^ abPeregrine A (March 2012). "Hookworms in Small Animals". The Merck Veterinary Manual. Archived from the original on 2012-07-11. Retrieved March 20, 2013.
^Ghosh K, Hotez, P (January 1999). "Antibody-Dependent Reductions in Mouse Hookworm Burden after Vaccination with Ancylostoma caninum Secreted Protein 1". J Infect Dis. 180 (5): 1674–1681. doi:10.1086/315059. PMID 10515831. S2CID 17298045.
^ abCheng T (1986). General Parasitology (2nd ed.). Academic Press. pp. 93, 508. ISBN 978-0121707552.
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