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Oxfendazole information


Oxfendazole
Clinical data
AHFS/Drugs.comInternational Drug Names
ATCvet code
  • QP52AC02 (WHO)
Identifiers
IUPAC name
  • Methyl N-[6-(benzenesulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate
CAS Number
  • 53716-50-0
PubChem CID
  • 40854
ChemSpider
  • 37316
UNII
  • OMP2H17F9E
ChEMBL
  • ChEMBL42442
CompTox Dashboard (EPA)
  • DTXSID9044112 Edit this at Wikidata
ECHA InfoCard100.053.358 Edit this at Wikidata
Chemical and physical data
FormulaC15H13N3O3S
Molar mass315.35 g·mol−1

Oxfendazole is a broad spectrum benzimidazole anthelmintic. Its main use is for protecting livestock against roundworm, strongyles and pinworms.[1][2] Oxfendazole is the sulfoxide metabolite of fenbendazole.

Oxfendazole is an anthelmintic (wormer) compound used in veterinary practice. It comes under the chemical class of the benzimidazoles. This drug is barely used in horses,[3] goats, sheep, and cattle. It is very scarcely applied on dogs and cats. The drug for livestock is majorly available in the form of pills, tablets, drenches, bolus, etc. They are meant for oral consumption. Several drenches are allowed for intraruminal injection in some of the countries. Few countries also prefer injectables and pour-ons. For pet dogs, the drug is available in the form of drenches.

  1. ^ "Oxfendazole".
  2. ^ Gonzalez AE, Codd EE, Horton J, Garcia HH, Gilman RH (January 2019). "Oxfendazole: a promising agent for the treatment and control of helminth infections in humans". Expert Review of Anti-infective Therapy. 17 (1): 51–56. doi:10.1080/14787210.2018.1555241. PMC 6376865. PMID 30501436.
  3. ^ Duncan JL, Reid JF (October 1978). "An evaluation of the efficacy of oxfendazole against the common nematode parasites of the horse". The Veterinary Record. 103 (15): 332–334. doi:10.1136/vr.103.15.332. PMID 364817.

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Oxfendazole

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against roundworm, strongyles and pinworms. Oxfendazole is the sulfoxide metabolite of fenbendazole. Oxfendazole is an anthelmintic (wormer) compound used...

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Fenbendazole

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proposed. Fenbendazole is metabolized in the liver to oxfendazole, which is anthelmintic too; oxfendazole partially gets reduced back to fenbendazole in the...

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Benzimidazole

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albendazole, ciclobendazole, fenbendazole, flubendazole, mebendazole, oxfendazole, oxibendazole, triclabendazole, and thiabendazole. These drugs work by...

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Deworming

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larvae; adult large strongyles; ascarids; bots Benzimidazoles Fenbendazole Oxfendazole Mebendazole Cyathostomes (adult small strongyles); migrating large strongyle...

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Cysticercosis

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human and porcine populations. It is feasible because treating pigs with oxfendazole has been shown to be effective and once treated, pigs are protected from...

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Praziquantel

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species It may cause problems in dogs with MDR1 mutations. Fenbendazole Oxfendazole Nocodazole "Product monograph brand safety updates". Health Canada. February...

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ATCvet code QP52

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QP52AB51 Metrifonate, combinations QP52AC01 Triclabendazole QP52AC02 Oxfendazole QP52AC03 Parbendazole QP52AC04 Thiophanate QP52AC05 Febantel QP52AC06...

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Tiabendazole

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pharmaceutical drugs, including albendazole, cambendazole, fenbendazole, oxfendazole, mebendazole, and flubendazole. Fungicide use in the United States List...

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Moniezia expansa

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(1990). "Comparative efficacy of praziquantel, albendazole, febantel and oxfendazole against Moniezia expansa". The Veterinary Record. 127 (14): 353–4. PMID 2260242...

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Cattle drenching

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their easy administration. The active ingredients used are albendazole, oxfendazole, triclabendazole and fenbendazole. Triclabendazole is the most commonly...

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Musca vetustissima

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repopulate Australia each spring. In a study, a mixture of levamisole and oxfendazole killed larvae in sheep feces. Dung beetle "Musca vetustissima, the Australian...

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Raillietina

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Broad-spectrum anthelmintics such as albendazole, fenbendazole, praziquantel, oxfendazole and niclosamide are all effective against the different species. The...

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Raillietina tetragona

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treated birds showed no clinical complications at various doses tested. Oxfendazole and niclosamide are equally effective and safe. The most effective control...

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Cooperia oncophora

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in clearing infection, including albendazole, febantel, fenbendazole, oxfendazole. Moreover, levamisole and several macrocyclic lactones (e.g. abamectin...

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