Alphapolyomavirus model with a non-enveloped capsid and a T = 7d icosahedral symmetry at a 50 nm diameter scale.
Virus classification
(unranked):
Virus
Realm:
Monodnaviria
Kingdom:
Shotokuvirae
Phylum:
Cossaviricota
Class:
Papovaviricetes
Order:
Sepolyvirales
Family:
Polyomaviridae
Genus:
Alphapolyomavirus
Alphapolyomavirus is one of eight genera of non-enveloped dsDNA viruses in the polyomaviridae family.[1][2] Member viruses primarily infect humans and other mammals.[3] Transmission of the virus in humans is primarily spread via direct contact with parents or other high-contact individuals as children.[4][5]
The primary alphapolyomavirus that is of clinical significance to humans is Merkel cell polyomavirus (Human polyomavirus 5, MCV, or MCPyV). The apparent oncogenicity of MCPyV[6] similar to other cancer-causing viruses such as HPV, Epstein-Barr virus, and Hepatitis C virus[7] is a main area of research for the scientific community.
^Kunitake, T; Kitamura, T; Guo, J; Taguchi, F; Kawabe, K; Yogo, Y (Jun 1995). "Parent-to-child transmission is relatively common in the spread of the human polyomavirus JC virus". Journal of Clinical Microbiology. 33 (6): 1448–1451. doi:10.1128/jcm.33.6.1448-1451.1995. ISSN 0095-1137. PMC 228193. PMID 7650165.
^Boothpur, Raghavender; Brennan, Daniel C. (Apr 2010). "Human Polyoma Viruses and Disease with Emphasis on Clinical BK and JC". Journal of Clinical Virology. 47 (4): 306–312. doi:10.1016/j.jcv.2009.12.006. ISSN 1386-6532. PMC 3774018. PMID 20060360.
^Spurgeon, Megan E.; Lambert, Paul F. (2013-01-05). "Merkel Cell Polyomavirus: A Newly Discovered Human Virus with Oncogenic Potential". Virology. 435 (1): 118–130. doi:10.1016/j.virol.2012.09.029. ISSN 0042-6822. PMC 3522868. PMID 23217622.
asymptomatically infected immunocompromised individuals. "Genus: Alphapolyomavirus" (html). International Committee on Taxonomy of Viruses (ICTV). Retrieved...
The BK virus, also known as Human polyomavirus 1, is a member of the polyomavirus family. Past infection with the BK virus is widespread, but significant...
Human polyomavirus 2, commonly referred to as the JC virus or John Cunningham virus, is a type of human polyomavirus (formerly known as papovavirus). It...
avian subset into the genus Gammapolyomavirus. The six genera are: Alphapolyomavirus Betapolyomavirus Deltapolyomavirus Epsilonpolyomavirus Gammapolyomavirus...
Taxonomy of Viruses classified MPyV as the type species of the genus Alphapolyomavirus under its new official name Mus musculus polyomavirus 1. Stehle, T;...
International Committee on Taxonomy of Viruses classified HaPyV in the genus Alphapolyomavirus, whose type species is mouse polyomavirus (MPyV). HaPyV and MPyV are...
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