It generally occurs in chronic alcoholics or those who binge drink[2]
Specialty
Internal medicine
Symptoms
Abdominal pain, vomiting, agitation, fast respiratory rate, specific "fruity" smell[2]
Risk factors
Alcoholism, binge drinking[2]
Diagnostic method
Based on symptoms[2]
Differential diagnosis
Other causes of high anion gap metabolic acidosis (diabetic ketoacidosis, toxic alcohol ingestion, starvation ketosis), pancreatitis[2][3]
Treatment
Intravenous fluids, thiamine[2]
Prognosis
Good with treatment[1]
Alcoholic ketoacidosis (AKA) is a specific group of symptoms and metabolic state related to alcohol use.[3] Symptoms often include abdominal pain, vomiting, agitation, a fast respiratory rate, and a specific "fruity" smell.[2] Consciousness is generally normal.[1] Complications may include sudden death.[1]
AKA most commonly occurs in long term alcoholics and less commonly in those who binge drink.[2] Onset is generally after a decreased ability to eat for a few days.[2] Diagnosis is generally based on symptoms.[2] Blood sugar levels are often normal or only mildly increased.[2] Other conditions that may present similarly include other causes of high anion gap metabolic acidosis including diabetic ketoacidosis.[2]
Treatment is generally with intravenous normal saline and intravenous sugar solution.[2] Thiamine and measures to prevent alcohol withdrawal are also recommended.[2] Treatment of low blood potassium may also be required.[2] Those who are affected are most frequently between the ages of 20 and 60.[2] The condition was initially recognized in 1940 and named in 1971.[3]
Alcoholicketoacidosis (AKA) is a specific group of symptoms and metabolic state related to alcohol use. Symptoms often include abdominal pain, vomiting...
acidosis. Altered mental status is more common in diabetic than alcoholicketoacidosis. Ketoacidosis is caused by the uncontrolled production of ketone bodies...
problems or irregularity of the menstrual cycle, and early menopause. Alcoholicketoacidosis can occur in individuals who chronically misuse alcohol and have...
anion gap metabolic acidosis are: ketoacidosis, lactic acidosis, kidney failure, and toxic ingestions. Ketoacidosis can occur as a complication of diabetes...
Headings (MeSH) McGuire, L. C; Cruickshank, A. M; Munro, P. T (2006). "Alcoholicketoacidosis". Emergency Medicine Journal. 23 (6): 417–420. doi:10.1136/emj.2004...
associated problems such as electrolyte abnormalities, pancreatitis, and alcoholic hepatitis. Prevention is by treating withdrawal symptoms using similarly...
Mihai, B; Lăcătuşu, C; Graur, M (April–June 2008). "Alcoholicketoacidosis" [Alcoholicketoacidosis]. Revista Medico-chirurgicală̆ A Societă̆ţ̜ii de Medici...
resulting in ketoacidosis. Ketoacidosis is known to occur in untreated type I diabetes (see diabetic ketoacidosis) and in alcoholics after prolonged...
American Kitefliers Association Australian Karting Association Alcoholicketoacidosis, a medical condition A retired US Navy hull classification symbol:...
gluconeogenesis, especially in children, and may cause lactic acidosis, ketoacidosis, and acute kidney injury. Metabolic acidosis is compounded by respiratory...
theophylline, or from conditions such as uremia or diabetic and alcoholicketoacidosis. The diagnosis of ethylene glycol poisoning should be considered...
relapse. Heavy alcohol consumption while in a hunger state can cause alcoholicketoacidosis, a life-threatening metabolic derailment. According to the World...
Small amounts of isopropyl alcohol are produced in the body in diabetic ketoacidosis. Indirect hydration reacts propene with sulfuric acid to form a mixture...
exposure to other toxic alcohols, serotonin syndrome, and diabetic ketoacidosis. Early treatment increases the chance of a good outcome. Treatment consists...
such as sepsis, traumatic brain injury, and diabetic ketoacidosis. Using thiamine on septic alcoholics seems to reduce the rate of death. Alcohol intoxication...
induce primary respiratory distress in the newborn period, as well as ketoacidosis.[citation needed] Neurological manifestations of hypoglycemia are less...
Symptoms of ketoacidosis include nausea, vomiting, abdominal pain, tiredness, and trouble breathing. To lessen the risk of developing ketoacidosis after surgery...
processes. It is normally present in blood and urine. People with diabetic ketoacidosis produce it in larger amounts. Ketogenic diets that increase ketone bodies...
electrolyte imbalance (Namely hypokalemia and hypercalcemia) diabetic ketoacidosis (DKA), and other causes of metabolic acidosis hypothyroidism diabetes...
acid catabolism, inhibition of the citric acid cycle, lactic acidosis, ketoacidosis, hyperuricemia, disturbance in cortisol and androgen metabolism and increased...
excretion of uric acid by promoting dehydration and (rarely) clinical ketoacidosis. High dietary intake of fructose contributes significantly to hyperuricemia...
can cause many complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications...
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