Process of addition of silyl group(s) to compounds
Not to be confused with silanization or sialylation.
Silylation is the introduction of one or more (usually) substituted silyl groups (R3Si) to a molecule. Silylations are core methods for production of organosilicon chemistry. Silanization involves similar methods but usually refers to attachment of silyl groups to solids.[1]
^Pape, Peter G. (2017). "Silylating Agents". Kirk-Othmer Encyclopedia of Chemical Technology. pp. 1–15. doi:10.1002/0471238961.1909122516011605.a01.pub3. ISBN 9780471238966.
Silylation is the introduction of one or more (usually) substituted silyl groups (R3Si) to a molecule. Silylations are core methods for production of organosilicon...
laboratory glassware, making the surfaces more lipophilic. By the process of silylation, polar functional groups such as alcohols and amines readily undergo reaction...
rn01923. ISBN 9780470842898. Stalling DL, Gehrke CW, Zumwalt RW. A new silylation reagent for amino acids bis(trimethylsilyl)trifluoroacetamide (BSTFA)...
trifluoromethanesulfonic acid. It is commonly used as a Lewis acid catalyst, e.g. in silylations. A white powder, zinc triflate is commercially available, though some...
which all have an abundance of hydroxyl groups. Silanization differs from silylation, which usually refers to attachment of organosilicon groups to molecular...
as a result; thus, the development of a one-pot, one-step method for silylation and nucleoside synthesis represented a significant advance. The combination...
Volumes, vol. 8, p. 616. Kuwajima, I.; Nakamura, E.; Hashimoto, K. (1990). "Silylation of Ketones with Ethyl Trimethylsilacetate: (Z)-3-Trimethylsiloxy-2-Pentene"...
chloride. Related to its tendency to hydrolyze, TMSOTf is effective for silylation of alcohols: (CH3)3SiO3SCF3 + ROH + Et3N → ROSi(CH3)3Si + [Et3NH]O3SCF3...
Enolates can be trapped by the addition of electrophiles at oxygen. Silylation gives silyl enol ether. Acylation gives esters such as vinyl acetate....
("carbodiimide" tautomer). The N≡C–NH2 form dominates, but in a few reactions (e.g. silylation) the diimide form appears to be important. Cyanamide dimerizes to give...
adulteration by added sugars with these methods. Derivatization using silylation reagents is commonly used. Also, the proportions of di- and trisaccharides...
Wilson, Jake W.; Hartwig, John F. (2023). "Transition-Metal-Catalyzed Silylation and Borylation of C–H Bonds for the Synthesis and Functionalization of...
and Grignard reagents with chlorosilanes. In some cases dehydrogenative silylation is another method. Ring, M. A.; O'Neal, H. E.; Rickborn, S. F.; Sawrey...
thermodynamically stable benzylic enolate. Enolates can be trapped by acylation and silylation, which occur at oxygen. Silyl enol ethers are common reagents in organic...
equivalents with silyl halides (typically trimethylsilyl chloride, tmsCl). Silylation of 2-lithio-1,3-dithiane, followed by hydrolysis of the dithioacetal group...
equilibrium with the ring-opened enolate-isonitrile, which can be trapped by silylation. Electrophilic aromatic substitution takes place at C5, but requiring...
installed and removed very selectively under mild conditions. Commonly silylation of alcohols requires a silyl chloride and an amine base. One reliable...
Lactone opening was done using lithium methoxide in methanol and then silylation to give a separable mixture of the starting lactone and the silyl ether...
Syntheses, Coll. Vol. 6, p.440; Vol. 57, p.50. Online version Identification of Silylation Artifacts in Derivatization Reactions for Gas Chromatography...
is similar to dichloromethane in standard acylation, tosylation, and silylation reactions. The dielectric constants for dichloromethane and trifluorotoluene...
"Efficient formation and cleavage of disilanes by potassium-graphite. Silylation with silyl metal reagents". Journal of Organometallic Chemistry. 354:...
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