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Accelerated failure time model information


In the statistical area of survival analysis, an accelerated failure time model (AFT model) is a parametric model that provides an alternative to the commonly used proportional hazards models. Whereas a proportional hazards model assumes that the effect of a covariate is to multiply the hazard by some constant, an AFT model assumes that the effect of a covariate is to accelerate or decelerate the life course of a disease by some constant. There is strong basic science evidence from C. Elegans experiments by Stroustrup et al.[1] indicating that AFT models are the correct model for biological survival processes.

  1. ^ Stroustrup, Nicholas (16 January 2016). "The temporal scaling of Caenorhabditis elegans ageing". Nature. 530 (7588): 103–107. doi:10.1038/nature16550. PMC 4828198.

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