ARPC1B information

ARPC1B
Identifiers
Aliases	ARPC1B, ARC41, p40-ARC, p41-ARC, actin related protein 2/3 complex subunit 1B, PLTEID, IMD71
External IDs	OMIM: 604223; MGI: 1343142; HomoloGene: 4179; GeneCards: ARPC1B; OMA:ARPC1B - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	99,394,816 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	145,067,515 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; blood; ; spleen; ; lymph node; ; appendix; ; upper lobe of left lung; ; mucosa of transverse colon; ; right lung; ; duodenum;
	Top expressed in
	granulocyte; ; stroma of bone marrow; ; mesenteric lymph nodes; ; gastrula; ; yolk sac; ; blastocyst; ; lip; ; tibiofemoral joint; ; migratory enteric neural crest cell; ; endothelial cell of lymphatic vessel;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin filament binding; actin binding; structural constituent of cytoskeleton; protein-containing complex binding; protein binding;
Cellular component	cytoplasm; cytosol; arp2/3 protein complex; extracellular exosome; cytoskeleton; focal adhesion; actin cytoskeleton; tubulobulbar complex; nucleus;
Biological process	Arp2/3 complex-mediated actin nucleation; ephrin receptor signaling pathway; regulation of actin filament polymerization; Fc-gamma receptor signaling pathway involved in phagocytosis; response to estrogen; response to estradiol;
	Sources:Amigo / QuickGO
Orthologs
	10095
	11867
	ENSG00000130429
	ENSMUSG00000029622
	O15143
	Q9WV32
	NM_005720
	NM_023142
	NP_005711
	NP_075631
	Wikidata
View/Edit Human	View/Edit Mouse

Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000130429 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029622 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ (Jul 1997). "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly". The Journal of Cell Biology. 138 (2): 375–84. doi:10.1083/jcb.138.2.375. PMC 2138188. PMID 9230079.
^ Machesky LM, Reeves E, Wientjes F, Mattheyse FJ, Grogan A, Totty NF, Burlingame AL, Hsuan JJ, Segal AW (Nov 1997). "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins". The Biochemical Journal. 328 ( Pt 1) (1): 105–12. doi:10.1042/bj3280105. PMC 1218893. PMID 9359840.
^ "Entrez Gene: ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000130429 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029622 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9230079-5] Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ (Jul 1997). "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly". The Journal of Cell Biology. 138 (2): 375–84. doi:10.1083/jcb.138.2.375. PMC 2138188. PMID 9230079.

[pmid9359840-6] Machesky LM, Reeves E, Wientjes F, Mattheyse FJ, Grogan A, Totty NF, Burlingame AL, Hsuan JJ, Segal AW (Nov 1997). "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins". The Biochemical Journal. 328 ( Pt 1) (1): 105–12. doi:10.1042/bj3280105. PMC 1218893. PMID 9359840.

[entrez-7] "Entrez Gene: ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa".

ARPC1B information

and 7 Related for: ARPC1B information

ARPC1B

WD40 repeat

Aleixo Muise

Stress granule

List of primary immunodeficiencies

ARPC1A

PAK1