SRP-dependent cotranslational protein targeting to membrane
viral transcription
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
translational initiation
protein biosynthesis
rRNA processing
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
6202
20116
Ensembl
ENSG00000142937
ENSMUSG00000047675
UniProt
P62241
P62242
RefSeq (mRNA)
NM_001012
NM_009098
RefSeq (protein)
NP_001003
NP_033124
Location (UCSC)
Chr 1: 44.78 – 44.78 Mb
Chr 4: 117.01 – 117.01 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
40S ribosomal protein S8 is a protein that in humans is encoded by the RPS8 gene.[5][6]
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000142937 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000047675 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Davies B, Fried M (Mar 1993). "The structure of the human intron-containing S8 ribosomal protein gene and determination of its chromosomal location at 1p32-p34.1". Genomics. 15 (1): 68–75. doi:10.1006/geno.1993.1011. PMID 8432552.
^ ab"Entrez Gene: RPS8 ribosomal protein S8".
and 4 Related for: 40S ribosomal protein S8 information
40SribosomalproteinS8 is a protein that in humans is encoded by the RPS8 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of...
A ribosomalprotein (r-protein or rProtein) is any of the proteins that, in conjunction with rRNA, make up the ribosomal subunits involved in the cellular...
small subunit (40S) and large subunit (60S) according to their sedimentation coefficients. Both subunits contain dozens of ribosomalproteins arranged on...
described and assembled in a unified mathematical model: Cap-40S initiation inhibition; 60S Ribosomal unit joining inhibition; Elongation inhibition; Ribosome...