40S ribosomal protein S7 information

RPS7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5A2Q, 5AJ0, 3J7P, 4KZX, 4UJE, 4KZY, 4D5L, 4KZZ, 3J7R, 4UJD, 5FLX, 4D61, 4UJC
Identifiers
Aliases	RPS7, DBA8, S7, ribosomal protein S7, eS7
External IDs	OMIM: 603658; MGI: 1333818; HomoloGene: 107159; GeneCards: RPS7; OMA:RPS7 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	3,580,920 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	28,685,952 bp
RNA expression pattern
	Top expressed in
	gonad; ; left ovary; ; granulocyte; ; ventricular zone; ; islet of Langerhans; ; right ovary; ; rectum; ; lymph node; ; smooth muscle tissue; ; ganglionic eminence;
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; lens; ; lip; ; yolk sac; ; thymus; ; morula; ; spleen; ; ovary; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of ribosome; protein binding; RNA binding; mRNA 3'-UTR binding; mRNA 5'-UTR binding; ubiquitin ligase inhibitor activity; protein kinase binding; poly(U) RNA binding;
Cellular component	cytosol; ribosome; membrane; focal adhesion; intracellular anatomical structure; microtubule organizing center; nucleolus; extracellular exosome; cytoskeleton; nucleus; nucleoplasm; extracellular matrix; cytoplasm; 90S preribosome; small-subunit processome; centrosome; cytosolic small ribosomal subunit; protein-containing complex; synapse; ribonucleoprotein complex;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit biogenesis; rRNA processing; protein biosynthesis; cytoplasmic translation; positive regulation of gene expression; protein stabilization; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; negative regulation of ubiquitin protein ligase activity; negative regulation of ubiquitin-dependent protein catabolic process; neural tube closure; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	6201
	20115
	ENSG00000171863
	ENSMUSG00000061477
	P62081
	P62082
	NM_001011
	NM_011300
	NP_001002
	NP_035430
	Wikidata
View/Edit Human	View/Edit Mouse

40S ribosomal protein S7 is a protein that in humans is encoded by the RPS7 gene.^[5]^[6]^[7]

In eukaryotes, ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171863 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061477 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Annilo T, Laan M, Stahl J, Metspalu A (Jan 1996). "The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25". Gene. 165 (2): 297–302. doi:10.1016/0378-1119(95)00576-R. PMID 8522193.
^ Gorbea C, Taillandier D, Rechsteiner M (Feb 2000). "Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7" (PDF). J Biol Chem. 275 (2): 875–82. doi:10.1074/jbc.275.2.875. PMID 10625621.
^ ^a ^b "Entrez Gene: RPS7 ribosomal protein S7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171863 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000061477 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8522193-5] Annilo T, Laan M, Stahl J, Metspalu A (Jan 1996). "The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25". Gene. 165 (2): 297–302. doi:10.1016/0378-1119(95)00576-R. PMID 8522193.

[pmid10625621-6] Gorbea C, Taillandier D, Rechsteiner M (Feb 2000). "Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7" (PDF). J Biol Chem. 275 (2): 875–82. doi:10.1074/jbc.275.2.875. PMID 10625621.

[entrez-7] "Entrez Gene: RPS7 ribosomal protein S7".

40S ribosomal protein S7 information

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