40S ribosomal protein S25 information

RPS25
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5A2Q, 5AJ0, 5FLX
Identifiers
Aliases	RPS25, S25, ribosomal protein S25
External IDs	OMIM: 180465; MGI: 1922867; HomoloGene: 133893; GeneCards: RPS25; OMA:RPS25 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	119,018,691 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	44,321,724 bp
RNA expression pattern
	Top expressed in
	left ovary; ; right ovary; ; Achilles tendon; ; pituitary gland; ; anterior pituitary; ; right uterine tube; ; gastric mucosa; ; thyroid gland; ; left lobe of thyroid gland; ; right lobe of thyroid gland;
	Top expressed in
	morula; ; embryo; ; blastocyst; ; embryo; ; ventricular zone; ; yolk sac; ; lip; ; genital tubercle; ; tail of embryo; ; granulocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; RNA binding; structural constituent of ribosome;
Cellular component	cytosol; ribosome; cytosolic small ribosomal subunit; nucleolus; small ribosomal subunit; extracellular exosome; nucleus; nucleoplasm; extracellular matrix; postsynaptic density;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; rRNA processing; protein biosynthesis;
	Sources:Amigo / QuickGO
Orthologs
	6230
	75617
	ENSG00000118181
	ENSMUSG00000009927
	P62851
	P62852
	NM_001028
	NM_024266
	NP_001019
	NP_077228
	Wikidata
View/Edit Human	View/Edit Mouse

40S ribosomal protein S25 (eS25) is a protein that in humans is encoded by the RPS25 gene.^[5]^[6]

Ribosomes are cellular macromolecules that catalyze protein synthesis across all kingdoms of life. The eukaryotic ribosome consists of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 distinct proteins. The RPS25 gene encodes the eukaryote-specific ribosomal protein eS25 that is a component of the 40S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000118181 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000009927 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Li ML, Latoud C, Center MS (November 1991). "Cloning and sequencing a cDNA encoding human ribosomal protein S25". Gene. 107 (2): 329–33. doi:10.1016/0378-1119(91)90335-9. PMID 1748303.
^ ^a ^b "Entrez Gene: RPS25 ribosomal protein S25".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000118181 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000009927 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1748303-5] Li ML, Latoud C, Center MS (November 1991). "Cloning and sequencing a cDNA encoding human ribosomal protein S25". Gene. 107 (2): 329–33. doi:10.1016/0378-1119(91)90335-9. PMID 1748303.

[entrez-6] "Entrez Gene: RPS25 ribosomal protein S25".

40S ribosomal protein S25 information

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