Utilization of 3D printing to fabricate biomedical parts
Different models of 3D printing tissue and organs.
Three dimensional (3D) bioprinting is the utilization of 3D printing–like techniques to combine cells, growth factors, bio-inks, and biomaterials to fabricate functional structures that were traditionally used for tissue engineering applications but in recent times have seen increased interest in other applications such as biosensing, and environmental remediation.[1][2][3] Generally, 3D bioprinting utilizes a layer-by-layer method to deposit materials known as bio-inks to create tissue-like structures that are later used in various medical and tissue engineering fields.[4][5] 3D bioprinting covers a broad range of bioprinting techniques and biomaterials. Currently, bioprinting can be used to print tissue and organ models to help research drugs and potential treatments.[6] Nonetheless, translation of bioprinted living cellular constructs into clinical application is met with several issues due to the complexity and cell number necessary to create functional organs.[7] However, innovations span from bioprinting of extracellular matrix to mixing cells with hydrogels deposited layer by layer to produce the desired tissue.[8] In addition, 3D bioprinting has begun to incorporate the printing of scaffolds which can be used to regenerate joints and ligaments.[9] Apart from these, 3D bioprinting has recently been used in environmental remediation applications, including the fabrication of functional biofilms that host functional microorganisms that can facilitate pollutant removal.[10]
^Murphy SV, Atala A (August 2014). "3D bioprinting of tissues and organs". Nature Biotechnology. 32 (8): 773–785. doi:10.1038/nbt.2958. ISSN 1546-1696. PMID 25093879. S2CID 22826340.
^Lehner BA, Schmieden DT, Meyer AS (March 1, 2017). "A Straightforward Approach for 3D Bacterial Printing". ACS Synthetic Biology. 6 (7): 1124–1130. doi:10.1021/acssynbio.6b00395. ISSN 2161-5063. PMC 5525104. PMID 28225616.
^Cite error: The named reference :0 was invoked but never defined (see the help page).
^Roche CD, Brereton RJ, Ashton AW, Jackson C, Gentile C (2020). "Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery". European Journal of Cardio-Thoracic Surgery. 58 (3): 500–510. doi:10.1093/ejcts/ezaa093. PMC 8456486. PMID 32391914.
^Chimene D, Lennox KK, Kaunas RR, Gaharwar AK (2016). "Advanced Bioinks for 3D Printing: A Materials Science Perspective". Annals of Biomedical Engineering. 44 (6): 2090–2102. doi:10.1007/s10439-016-1638-y. PMID 27184494. S2CID 1251998.
^Hinton TJ, Jallerat Q, Palchesko RN, Park JH, Grodzicki MS, Shue HJ, et al. (October 2015). "Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels". Science Advances. 1 (9): e1500758. Bibcode:2015SciA....1E0758H. doi:10.1126/sciadv.1500758. PMC 4646826. PMID 26601312.
^Murphy SV, De Coppi P, Atala A (April 2020). "Opportunities and challenges of translational 3D bioprinting". Nature Biomedical Engineering. 4 (4): 370–380. doi:10.1038/s41551-019-0471-7. ISSN 2157-846X. PMID 31695178. S2CID 207912104.
^Roche CD, Sharma P, Ashton AW, Jackson C, Xue M, Gentile C (2021). "Printability, durability, contractility and vascular network formation in 3D bioprinted cardiac endothelial cells using alginate–gelatin hydrogels". Frontiers in Bioengineering and Biotechnology. 9: 110. doi:10.3389/fbioe.2021.636257. PMC 7968457. PMID 33748085.
^Nakashima Y, Okazak K, Nakayama K, Okada S, Mizu-uchi H (January 2017). "Bone and Joint Diseases in Present and Future". Fukuoka Igaku Zasshi = Hukuoka Acta Medica. 108 (1): 1–7. PMID 29226660.
^Zhao T, Liu Y, Wu Y, Zhao M, Zhao Y (December 1, 2023). "Controllable and biocompatible 3D bioprinting technology for microorganisms: Fundamental, environmental applications and challenges". Biotechnology Advances. 69: 108243. doi:10.1016/j.biotechadv.2023.108243. ISSN 0734-9750. PMID 37647974. S2CID 261383630.
tissue engineering fields. 3Dbioprinting covers a broad range of bioprinting techniques and biomaterials. Currently, bioprinting can be used to print tissue...
Magnetic 3Dbioprinting is a methodology that employs biocompatible magnetic nanoparticles to print cells into 3D structures or 3D cell cultures. In this...
uses its internally developed NovoGen MMX Bioprinter for 3Dbioprinting. The company bioprints and markets human tissues as a means of accelerating the...
F.; Fuh, J. Y. H. (2016-03-01). "3Dbioprinting – An Ethical, Legal and Social Aspects (ELSA) framework". Bioprinting. 1–2: 11–21. doi:10.1016/j.bprint...
Steakholder Foods is a company which develops 3Dbioprinting technologies for usage in cellular agriculture. Based in Israel, it has a Belgian subsidiary...
that have been studied include bioprinting hydrogels with various Bio-ink (cell-laden microgel) materials and bioprinting implantable devices that mimic...
explored in the RecycleBot. 3Dbioprinting3D food printing 3D Manufacturing Format 3D printing marketplace 3D printing speed 3D printing in India AstroPrint...
limitations of bioprinting on Earth including magnetic field disruption and biostructure retention during the printing process. Microgravity bioprinting is one...
aspects of a field like 3D food printing. 3D Printing Multi-material 3D printing 3Dbioprinting3D drug printing 3D Scanning 3D Modelling Fused Deposition...
Ethics of bioprinting is a sub-field of ethics concerning bioprinting. Some of the ethical issues surrounding bioprinting include equal access to treatment...
surfaces, and rotating bioreactors, magnetic levitation, and magnetic 3Dbioprinting. Spheroids are a type of three-dimensional cell modeling that better...
with 3DBioprinting Solutions to culture meat on the International Space Station. This was done by extruding meat cells onto a scaffold using a 3D printer...
transplantation. 3Dbioprinting can be used to reconstruct tissue from various regions of the body. The precursor to the adoption of 3D printing in healthcare...
Potential Power of 3D-Bioprinting?". Engineering.com.{{cite web}}: CS1 maint: numeric names: authors list (link) "Chinese Scientists Are 3D Printing Ears and...
environments and do not compete for land or other human resources. 3DBioprinting of tissue engineering scaffolds for creating artificial tissues and...
PMC 5889544. PMID 29636985. Homan, Kimberly A.; Lewis, Jennifer A (2016). "Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips". Scientific...
environment. Collagen is also widely used as a bioink for 3Dbioprinting and biofabrication of 3D tissue models. The collagen protein is composed of a triple...
Bioreactor processes for maturation of 3D bioprinted tissue". In Thomas DJ, Jessop ZM, Whitaker IS (eds.). 3DBioprinting for Reconstructive Surgery. Woodhead...
ISSN 0099-9660. Retrieved 2021-10-20. "3Dbioprinting research aims to treat osteoarthritis with cartilage replacements". 3D Printing Industry. 2017-05-02. Retrieved...
vehicles in cancer treatment and their applications in wound dressing and 3Dbioprinting". Journal of Biological Engineering. 14 (8): 8. doi:10.1186/s13036-020-0227-7...
whose 3D bioprinters and bio-links can bioprint tissue 10 times faster that legacy bioprinting methods. In 2021, the company was acquired by 3D Systems...
strategies for engineered negligible senescence, nanomedicine, and 3Dbioprinting. Variants of human genetic engineering with so far limited usage include...
used as the building block material, or the "ink" for the magnetic 3Dbioprinting process. Standard monolayer cell culturing on tissue culture plastic...
Kengla; Ko, In Kap; Lee, Sang Jin; Kang, Hyun-Wook (March 2016). "A 3Dbioprinting system to produce human-scale tissue constructs with structural integrity"...
January 2018, Cellink announced a collaboration with Ctibiotech to boost 3Dbioprinting technology for cancer research. The company's revenue totaled $4.88...
to carry drugs or cells for applications in tissue regeneration or 3Dbioprinting. Hydrogels with reversible chemistry are required to allow for fluidization...
unveiled the world's first cell-based ribeye steak, produced through 3Dbioprinting. In May 2019, the company announced a US$12M funding round led by Vis...
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