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28S ribosomal RNA information


Mitochondrial 16S and nuclear 28S ribosomal DNA phylogenies of three species of mollusks belonging to the genus Waldo.

28S ribosomal RNA is the structural ribosomal RNA (rRNA) for the large subunit (LSU) of eukaryotic cytoplasmic ribosomes, and thus one of the basic components of all eukaryotic cells. It has a size of 25S in plants and 28S in mammals, hence the alias of 25S–28S rRNA.[1]

Combined with 5.8S rRNA to the 5' side, it is the eukaryotic nuclear homologue of the prokaryotic 23S and mitochondrial 16S ribosomal RNAs.[2][3][4]

  1. ^ Lodish, Harvey F.; Darnell, James E. (1995-01-01). Molecular cell biology. Scientific American Books. ISBN 978-0-7167-2380-6. OCLC 30783343.
  2. ^ Eperon, I. C.; Anderson, S.; Nierlich, D. P. (1980-07-31). "Distinctive sequence of human mitochondrial ribosomal RNA genes". Nature. 286 (5772): 460–467. Bibcode:1980Natur.286..460E. doi:10.1038/286460a0. PMID 6157106. S2CID 4262269.
  3. ^ Doris, Stephen M.; Smith, Deborah R.; Beamesderfer, Julia N.; Raphael, Benjamin J.; Nathanson, Judith A.; Gerbi, Susan A. (October 2015). "Universal and domain-specific sequences in 23S–28S ribosomal RNA identified by computational phylogenetics". RNA. 21 (10): 1719–1730. doi:10.1261/rna.051144.115. PMC 4574749. PMID 26283689.
  4. ^ Lafontaine, D. L. J.; Tollervey, D. (2001). "The function and synthesis of ribosomes". Nature Reviews Molecular Cell Biology. 2 (7): 514–520. doi:10.1038/35080045. hdl:1842/729. PMID 11433365. S2CID 2637106.

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28S ribosomal RNA

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28S ribosomal RNA is the structural ribosomal RNA (rRNA) for the large subunit (LSU) of eukaryotic cytoplasmic ribosomes, and thus one of the basic components...

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Ribosomal RNA

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Ribosomal ribonucleic acid (rRNA) is a type of non-coding RNA which is the primary component of ribosomes, essential to all cells. rRNA is a ribozyme...

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23S ribosomal RNA

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other rRNAs. The eukaryotic homolog of the 23S LSU rRNA is the 28S ribosomal RNA, with a region filled by the 5.8S ribosomal RNA. In general, rRNA has an...

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18S ribosomal RNA

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18S ribosomal RNA (abbreviated 18S rRNA) is a part of the ribosomal RNA in eukaryotes. It is a component of the Eukaryotic small ribosomal subunit (40S)...

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16S ribosomal RNA

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16S ribosomal RNA (or 16S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence...

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5S ribosomal RNA

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The 5S ribosomal RNA (5S rRNA) is an approximately 120 nucleotide-long ribosomal RNA molecule with a mass of 40 kDa. It is a structural and functional...

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LSU rRNA

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February 2015. "Homo sapiens RNA, 5.8S ribosomal N1 (RNA5-8SN1), ribosomal RNA". 3 July 2020. "Homo sapiens 28S ribosomal RNA (nuclear)". 10 November 1986...

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Ribosomal DNA

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Ribosomal DNA (rDNA) is a DNA sequence that codes for ribosomal RNA. These sequences regulate transcription initiation and amplification, and contain...

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RNA integrity number

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expression studies and traditionally has been evaluated using the 28S to 18S rRNA ratio, a method that has been shown to be inconsistent. This inconsistency...

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Ribosome biogenesis

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plants] or 28S [in mammals], 5.8S, and 5S rRNA and 46 ribosomal proteins) and a small 40S subunit (which contains the 18S rRNA and 33 ribosomal proteins)...

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Ribosome

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components: the small and large ribosomal subunits. Each subunit consists of one or more ribosomal RNA molecules and many ribosomal proteins (r-proteins). The...

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Nucleolus organizer region

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RNR4, and RNR5 respectively. These regions code for 5.8S, 18S, and 28S ribosomal RNA. The NORs are "sandwiched" between the repetitive, heterochromatic...

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RNA

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RNA (tRNA) molecules to deliver amino acids to the ribosome, where ribosomal RNA (rRNA) then links amino acids together to form coded proteins. It has become...

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Mite

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among phyla and superphyla, while the ITS2, and the 18S ribosomal RNA and 28S ribosomal RNA genes, provide clues at deeper levels. Superorder Parasitiformes...

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Preribosomal RNA

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Preribosomal RNA (pre-rRNA) is the precursor to mature ribosomal RNA (rRNA), which is a component of ribosomes. Pre-rRNA is first transcribed from ribosomal DNA...

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R2 RNA element

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The R2 RNA element is a non-long terminal repeat (non-LTR) retrotransposable element that inserts at a specific site in the 28S ribosomal RNA (rRNA) genes...

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Internal transcribed spacer

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small-subunit ribosomal RNA (rRNA) and large-subunit rRNA genes in the chromosome or the corresponding transcribed region in the polycistronic rRNA precursor...

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Small nucleolar RNA SNORD38

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predicted to guides the methylation of 2'-O-ribose residues in 28S ribosomal RNA (rRNA). The mouse homologue of U38 (MBII-329) has also been identified...

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Small nucleolar RNA SNORD36

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substrate RNAs. U36 is encoded within the intron of ribosomal protein rpL7a, and has two regions of complementarity to 18S and 28S ribosomal RNA. This complementarity...

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RNR1

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RNA, ribosomal 1, also known as RNR1, is a human gene. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library...

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RNR3

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RNA, ribosomal 3, also known as RNR3, is a human gene. It is a minor isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex...

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Small nucleolar RNA SNORD88

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of 28S ribosomal RNA (rRNA) residue C3680. There is evidence that SNORD88 is processed into smaller fragments in a similar fashion to a microRNA and...

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Small nucleolar RNA SNORA58

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associated with GAR1 protein. snoRNA ACA58 is predicted to guide the pseudouridylation of U3823 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation...

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RNA polymerase I

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RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized...

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Fanconi anemia

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ribosomal subunit by processing pre-ribosomal RNA (pre-rRNA), the transcription of pre-rRNA by RNAPI, maintaining levels of the mature 28S ribosomal RNA...

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Small nucleolar RNA SNORD29

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gene). U29 is proposed to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue A4493. Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A...

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Small nucleolar RNA SNORD15

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site-specific 2'-O-methylation of substrate RNAs. U15 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue A3764. In humans there...

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