"28S" redirects here. For the isotope of sulfur (28S), see Sulfur-28.
RNA component of the large subunit of the eukaryotic ribosome
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28S ribosomal RNA is the structural ribosomal RNA (rRNA) for the large subunit (LSU) of eukaryotic cytoplasmic ribosomes, and thus one of the basic components of all eukaryotic cells. It has a size of 25S in plants and 28S in mammals, hence the alias of 25S–28S rRNA.[1]
Combined with 5.8S rRNA to the 5' side, it is the eukaryotic nuclear homologue of the prokaryotic 23S and mitochondrial 16S ribosomal RNAs.[2][3][4]
^Lodish, Harvey F.; Darnell, James E. (1995-01-01). Molecular cell biology. Scientific American Books. ISBN 978-0-7167-2380-6. OCLC 30783343.
^Eperon, I. C.; Anderson, S.; Nierlich, D. P. (1980-07-31). "Distinctive sequence of human mitochondrial ribosomal RNA genes". Nature. 286 (5772): 460–467. Bibcode:1980Natur.286..460E. doi:10.1038/286460a0. PMID 6157106. S2CID 4262269.
^Doris, Stephen M.; Smith, Deborah R.; Beamesderfer, Julia N.; Raphael, Benjamin J.; Nathanson, Judith A.; Gerbi, Susan A. (October 2015). "Universal and domain-specific sequences in 23S–28S ribosomal RNA identified by computational phylogenetics". RNA. 21 (10): 1719–1730. doi:10.1261/rna.051144.115. PMC 4574749. PMID 26283689.
^Lafontaine, D. L. J.; Tollervey, D. (2001). "The function and synthesis of ribosomes". Nature Reviews Molecular Cell Biology. 2 (7): 514–520. doi:10.1038/35080045. hdl:1842/729. PMID 11433365. S2CID 2637106.
28SribosomalRNA is the structural ribosomalRNA (rRNA) for the large subunit (LSU) of eukaryotic cytoplasmic ribosomes, and thus one of the basic components...
Ribosomal ribonucleic acid (rRNA) is a type of non-coding RNA which is the primary component of ribosomes, essential to all cells. rRNA is a ribozyme...
other rRNAs. The eukaryotic homolog of the 23S LSU rRNA is the 28SribosomalRNA, with a region filled by the 5.8S ribosomalRNA. In general, rRNA has an...
18S ribosomalRNA (abbreviated 18S rRNA) is a part of the ribosomalRNA in eukaryotes. It is a component of the Eukaryotic small ribosomal subunit (40S)...
16S ribosomalRNA (or 16S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence...
The 5S ribosomalRNA (5S rRNA) is an approximately 120 nucleotide-long ribosomalRNA molecule with a mass of 40 kDa. It is a structural and functional...
Ribosomal DNA (rDNA) is a DNA sequence that codes for ribosomalRNA. These sequences regulate transcription initiation and amplification, and contain...
expression studies and traditionally has been evaluated using the 28S to 18S rRNA ratio, a method that has been shown to be inconsistent. This inconsistency...
plants] or 28S [in mammals], 5.8S, and 5S rRNA and 46 ribosomal proteins) and a small 40S subunit (which contains the 18S rRNA and 33 ribosomal proteins)...
components: the small and large ribosomal subunits. Each subunit consists of one or more ribosomalRNA molecules and many ribosomal proteins (r-proteins). The...
RNR4, and RNR5 respectively. These regions code for 5.8S, 18S, and 28SribosomalRNA. The NORs are "sandwiched" between the repetitive, heterochromatic...
RNA (tRNA) molecules to deliver amino acids to the ribosome, where ribosomalRNA (rRNA) then links amino acids together to form coded proteins. It has become...
among phyla and superphyla, while the ITS2, and the 18S ribosomalRNA and 28SribosomalRNA genes, provide clues at deeper levels. Superorder Parasitiformes...
Preribosomal RNA (pre-rRNA) is the precursor to mature ribosomalRNA (rRNA), which is a component of ribosomes. Pre-rRNA is first transcribed from ribosomal DNA...
The R2 RNA element is a non-long terminal repeat (non-LTR) retrotransposable element that inserts at a specific site in the 28SribosomalRNA (rRNA) genes...
small-subunit ribosomalRNA (rRNA) and large-subunit rRNA genes in the chromosome or the corresponding transcribed region in the polycistronic rRNA precursor...
predicted to guides the methylation of 2'-O-ribose residues in 28SribosomalRNA (rRNA). The mouse homologue of U38 (MBII-329) has also been identified...
substrate RNAs. U36 is encoded within the intron of ribosomal protein rpL7a, and has two regions of complementarity to 18S and 28SribosomalRNA. This complementarity...
RNA, ribosomal 1, also known as RNR1, is a human gene. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library...
RNA, ribosomal 3, also known as RNR3, is a human gene. It is a minor isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex...
associated with GAR1 protein. snoRNA ACA58 is predicted to guide the pseudouridylation of U3823 of 28SribosomalRNA (rRNA). Pseudouridylation is the (isomerisation...
RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomalRNA (but not 5S rRNA, which is synthesized...
ribosomal subunit by processing pre-ribosomalRNA (pre-rRNA), the transcription of pre-rRNA by RNAPI, maintaining levels of the mature 28Sribosomal RNA...
site-specific 2'-O-methylation of substrate RNAs. U15 is predicted to guide the 2'O-ribose methylation of 28SribosomalRNA (rRNA) residue A3764. In humans there...