Protein-coding gene in the species Homo sapiens
ZMIZ1 Available structures PDB Ortholog search: PDBe RCSB
Identifiers Aliases ZMIZ1 , MIZ, RAI17, TRAFIP10, ZIMP10, hZIMP10, zinc finger MIZ-type containing 1, NEDDFSAExternal IDs OMIM: 607159; MGI: 3040693; HomoloGene: 10667; GeneCards: ZMIZ1; OMA:ZMIZ1 - orthologs Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q22.3 Start 79,068,966 bp[1] End 79,316,519 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A3 Start 25,459,609 bp[2] End 25,667,167 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in dorsal motor nucleus of vagus nerve tibia seminal vesicula inferior olivary nucleus ganglionic eminence endothelial cell synovial joint urethra vulva hair follicle
Top expressed in Rostral migratory stream gastrula genital tubercle stroma of bone marrow epithelium of stomach molar tail of embryo cumulus cell ventricular zone olfactory epithelium
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
zinc ion binding
metal ion binding
Cellular component
cytoplasm
nucleus
nuclear speck
intracellular membrane-bounded organelle
nucleoplasm
Biological process
vasculogenesis
heart morphogenesis
developmental growth
in utero embryonic development
regulation of transcription, DNA-templated
transcription, DNA-templated
vitellogenesis
artery morphogenesis
positive regulation of fibroblast proliferation
positive regulation of T cell differentiation
positive regulation of Notch signaling pathway
positive regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_001033402 NM_183208 NM_001310666
RefSeq (protein) Location (UCSC) Chr 10: 79.07 – 79.32 Mb Chr 14: 25.46 – 25.67 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Zinc finger MIZ domain-containing protein 1 is a protein that in humans is encoded by the ZMIZ1 gene.[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000108175 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000007817 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Entrez Gene: ZMIZ1 zinc finger, MIZ-type containing 1".
Last Update: 2022-10-17T11:46:06Z
domain-containing protein 1 is a protein that in humans is encoded by the ZMIZ1 gene. ZMIZ1 has been shown to interact with Androgen receptor. GRCh38: Ensembl...
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Last Update: 2024-04-20T13:59:21Z
allele called rs76518691) and NGF (the mutant allele called rs7523831). Both ZMIZ1 and NGF are associated with autoimmune responses and diseases, as well as...
Word Count : 4925
Last Update: 2024-06-27T00:04:03Z
receptor 2, Testicular receptor 4, TGFB1I1, TMF1, TRIM68, UBE2I, UXT, and ZMIZ1 . Membrane androgen receptor Discovery and development of antiandrogens GRCh38:...
Word Count : 9366
Last Update: 2023-12-31T21:36:49Z
still preserving its useful functions through the finding of a protein, ZMIZ1 , which activates the cancer function of Notch. In 2014, funding aided research...
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