Protein found in humans
XPR1 Available structures PDB Ortholog search: PDBe RCSB
Identifiers Aliases XPR1 , SYG1, X3, IBGC6, xenotropic and polytropic retrovirus receptor 1, SLC53A1External IDs OMIM: 605237 MGI: 97932 HomoloGene: 134226 GeneCards: XPR1 Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q25.3 Start 180,632,022 bp[1] End 180,890,279 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 G3|1 66.49 cM Start 155,151,447 bp[2] End 155,293,161 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence secondary oocyte endothelial cell pancreatic epithelial cell islet of Langerhans Brodmann area 23 right ventricle endometrium middle temporal gyrus bronchial epithelial cell
Top expressed in median eminence ventromedial nucleus arcuate nucleus habenula ascending aorta dorsomedial hypothalamic nucleus extensor digitorum longus muscle mammillary body triceps brachii muscle paraventricular nucleus of hypothalamus
More reference expression data
BioGPS
Gene ontology Molecular function
G protein-coupled receptor activity
transmembrane signaling receptor activity
phosphate ion transmembrane transporter activity
inositol hexakisphosphate binding
virus receptor activity
efflux transmembrane transporter activity
signaling receptor activity
Cellular component
integral component of membrane
membrane
intrinsic component of plasma membrane
plasma membrane
cytoplasm
Golgi apparatus
Biological process
viral entry into host cell
G protein-coupled receptor signaling pathway
response to virus
cellular phosphate ion homeostasis
phosphate ion transmembrane transport
phosphate ion transport
cellular response to phosphate starvation
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_004736 NM_001135669 NM_001328662
RefSeq (protein) NP_001129141 NP_001315591 NP_004727
Location (UCSC) Chr 1: 180.63 – 180.89 Mb Chr 1: 155.15 – 155.29 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Xenotropic and polytropic retrovirus receptor 1 is a protein that in humans is encoded by the XPR1 gene.
[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000143324 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026469 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: Xenotropic and polytropic retrovirus receptor 1". Retrieved 2017-03-31 .
Last Update: 2023-08-10T16:45:45Z
Xenotropic and polytropic retrovirus receptor 1 is a protein that in humans is encoded by the XPR1 gene. GRCh38: Ensembl release 89: ENSG00000143324 –...
Word Count : 181
Last Update: 2024-05-10T17:16:49Z
Stavrou, E. X.; Butler, L. M.; Renné, T. (2021). "Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate". Blood...
Word Count : 3276
Last Update: 2024-04-26T15:39:50Z
Jaagsiekte sheep retrovirus (JSRV) Koala retrovirus (KoRV) Mouse mammary tumor virus (MMTV) Murine leukemia virus (MLV) and xenotropic murine leukemia...
Word Count : 8298
Last Update: 2024-04-06T15:03:07Z
Non-ecotropic MLVs may be xenotropic (from xenos, "foreign", infecting non-mouse species), polytropic or modified polytropic (infecting a range of hosts...
Word Count : 1454
Last Update: 2023-08-26T15:30:24Z
XPR1 proteins: the xenotropic and polytropic retrovirus receptor confers susceptibility to infection with xenotropic and polytropic murine leukaemia viruses...
Word Count : 1314