William Withering FRS (17 March 1741 – 6 October 1799) was an English botanist, geologist, chemist, physician and first systematic investigator of the bioactivity of digitalis.
Withering was born in Wellington, Shropshire, the son of a surgeon.[1] He trained as a physician and studied medicine at the University of Edinburgh Medical School. He worked at Birmingham General Hospital from 1779. The story is that he noticed a person with dropsy (swelling from congestive heart failure) improve remarkably after taking a traditional herbal remedy; Withering became famous for recognising that the active ingredient in the mixture came from the foxglove plant.[2] The active ingredient is now known as digoxin, after the plant's scientific name. In 1785, Withering published An Account of the Foxglove and some of its Medical Uses, which contained reports on clinical trials and notes on digitalis's effects and toxicity.[3]
^"William Withering (1741-1799), a biographical sketch of a Birmingham Lunatic. - The James Lind Library". The James Lind Library. Retrieved 24 August 2017.
^Haughton, Claire (1980). Green Immigrants. New York: Harcourt, Brace, Jovanovich. pp. 133–134. ISBN 0-15-636492-1.
^William Withering, An Account of the Foxglove and some of its Medical Uses (Birmingham, England: M. Swinney, 1785).
WilliamWithering FRS (17 March 1741 – 6 October 1799) was an English botanist, geologist, chemist, physician and first systematic investigator of the...
James Keir, Joseph Priestley, William Small, Jonathan Stokes, James Watt, Josiah Wedgwood, John Whitehurst and WilliamWithering. While the society's meetings...
American colonies, the Medical School at the College of Philadelphia; WilliamWithering, the discoverer of digitalis; Sir Gilbert Blane, medical reformer...
a medication for heart failure. Its clinical use was pioneered by WilliamWithering, who recognized it "reduced dropsy", increased urine flow, and had...
drug used to treat dropsy. The story involved real-life physician WilliamWithering, who appeared to have learned of the value of the purple foxglove...
(Tarnowskie Góry and Tajno at Suwałki Region). Witherite was named after WilliamWithering (1741–1799) an English physician and naturalist who in 1784 published...
was first described in the English-speaking medical literature by WilliamWithering, in 1785, which is considered the beginning of modern therapeutics...
resulted in 27 deaths. The condition was first described in 1785 by WilliamWithering. Digoxin toxicity is often divided into acute or chronic toxicity...
(swollen ankles—a symptom of heart failure) following its discovery by WilliamWithering. Alongside diuretics, it was the mainstay of treatment for heart failure...
the chemical industry Thomas Day, 1768, eccentric and author Dr. WilliamWithering, 1775, the death of Dr. Small left an opening for a physician in the...
engine Joseph Priestley: laboratory equipment James Keir: crystals WilliamWithering: foxglove, with words from his book An Account of the Foxglove and...
Telford. David Brown (born 1987) is a British YouTuber and musician. WilliamWithering (1741 in Wellington - 1799) an English botanist, geologist, chemist...
with the introduction of digitalis into the practice of medicine was WilliamWithering. "Flavonoids". Micronutrient Information Center, Linus Pauling Institute...
opiates for acute shortage of breath due to heart failure. In 1785, WilliamWithering described the therapeutic uses of the foxglove genus of plants in...
with the introduction of digitalis into the practice of medicine was WilliamWithering. Da Silva C, et al. (2013). "The High Polyphenol Content of Grapevine...
Lunar Society Una White (1938/9–1997) – subject of public art-work WilliamWithering (1741–1799) – doctor, discoverer of digitalis Victoria Wood (1953–2016)...
baryta (in Latin). Also in the 18th century, English mineralogist WilliamWithering noted a heavy mineral in the lead mines of Cumberland, now known to...
clergy sprang involuntarily to his assistance but retreated with haste, so withering was the fire which flashed from those failing eyes." The Gladstones returned...
supposedly providing him with the inspiration behind The Two Towers. Dr WilliamWithering, physician, lived at Edgbaston Hall. John Wyndham, the science fiction...
as a plant collector and cataloguer. Stokes became associated with WilliamWithering (1741–1799), physician and botanist, who was a member of the influential...
as to where the fungi observed originated from. English botanist WilliamWithering disagreed with Sowerby's assumption that all three species were the...
century, much of clinical pharmacology was established by the work of WilliamWithering. Pharmacology as a scientific discipline did not further advance until...
toxicity produces nausea, vomiting, lethargy, confusion, and weakness. WilliamWithering is credited as the first to clinically investigate the plant as a...
boundaries of the Solar System for the first time in modern history. 1785: WilliamWithering: publishes the first definitive account of the use of foxglove (digitalis)...
Thomas Witherings (died 28 September 1651) was an English merchant and postal administrator who established the Royal Mail public letter service. He was...
"Fair Hill", the former home of Joseph Priestley, which the botanist WilliamWithering had renamed. He was Charles Darwin's half-cousin, sharing the common...
dark gray if impure. It was first recognized as a mineral species by WilliamWithering in 1783, who discovered it in the Parys copper-mine in Anglesey; the...
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