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The visual cycle is a process in the retina that replenishes the molecule retinal for its use in vision. Retinal is the chromophore of most visual opsins, meaning it captures the photons to begin the phototransduction cascade. When the photon is absorbed, the 11-cis retinal photoisomerizes into all-trans retinal as it is ejected from the opsin protein. Each molecule of retinal must travel from the photoreceptor cell to the RPE and back in order to be refreshed and combined with another opsin. This closed enzymatic pathway of 11-cis retinal is sometimes called Wald's visual cycle after George Wald (1906–1997), who received the Nobel Prize in 1967 for his work towards its discovery.
The visualcycle is a process in the retina that replenishes the molecule retinal for its use in vision. Retinal is the chromophore of most visual opsins...
The visualcycle is a circular enzymatic pathway, which is the front-end of phototransduction. It regenerates 11-cis-retinal. For example, the visual cycle...
that follows the isomerization and renewal of retinal is known as the visualcycle. Free 11-cis-retinal is photosensitive and carries its own spectral sensitivity...
also known as retinoid isomerohydrolase, is an enzyme of the vertebrate visualcycle that is encoded in humans by the RPE65 gene. RPE65 is expressed in the...
in the transduction of light into visual signals in the photoreceptor level of the retina (known as the visualcycle). Retinene2 is more formally known...
between those two cofactors. However, not all retinol dehydrogenases in visualcycle are identified, and this remains challenging to scientists due to the...
Visual Studio is an integrated development environment (IDE) developed by Microsoft. It is used to develop computer programs including websites, web apps...
molecule notable for its establishment of a new class of compounds known as visualcycle modulators (VCMs). Formulated as the hydrochloride salt, emixustat hydrochloride...
The estrous cycle (from Latin oestrus 'frenzy', originally from Ancient Greek οἶστρος (oîstros) 'gadfly') is a set of recurring physiological changes...
Retinol is an essential compound in the cycle of light-activated chemical reactions called the "visualcycle" that underlies vertebrate vision. Retinol...
isolation and purification of Retinol Binding Proteins involved in the visualcycle. The first biotinylated retinoid was synthesized in 2002 and was used...
that produce metabolites to open ion channels. Retinylidene protein VisualcycleVisual phototransduction Microbial rhodopsin Channelrhodopsins Illustration...
Visual or vision impairment (VI or VIP) is the partial or total inability of visual perception. In the absence of treatment such as corrective eyewear...
Visual thinking, also called visual or spatial learning or picture thinking, is the phenomenon of thinking through visual processing. Visual thinking has...
inverse is catalyzed by REH. The esters are also intermediates in the visualcycle: RPE65 isomerizes the retinyl part to 11-cis-retinal. Vitamin A palmitate...
the retinylidene group causes signal transduction in color vision (See visualcycle for details). There has been a long discussion that lysine, when administered...
A visual novel (VN) is a form of digital interactive fiction. Visual novels are often associated with the medium of video games, but are not always labeled...
Taxonomy of Visual Processes. Psychology Press. p. 389. ISBN 978-1-317-66895-4. Reike, Fred (2000). Vertebrae Phototransduction and the VisualCycle. Academic...
the ATP-binding cassette transporter (ABCA4) protein of the visual phototransduction cycle. Defective ABCA4 leads to improper shuttling of vitamin A throughout...
drawings, and artist's books, created by American visual artist and filmmaker Matthew Barney. The Cremaster Cycle was made over a period of eight years (1994–2002)...
encoded by the RDH8 gene. All-trans-retinol dehydrogenase (RDH8) is a visualcycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence...
Marcin; Palczewski, Krzysztof (11 July 2013). "Chemistry of the Retinoid (Visual) Cycle". Chemical Reviews. 114 (1): 194–232. doi:10.1021/cr400107q. PMC 3858459...
CycleBeads is a visual tool that was developed by the Institute for Reproductive Health at Georgetown University. This device helps women use the Standard...