VTI1B information

VTI1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2V8S
Identifiers
Aliases	VTI1B, VTI1, VTI1-LIKE, VTI1L, VTI2, v-SNARE, vti1-rp1, vesicle transport through interaction with t-SNAREs 1B
External IDs	OMIM: 603207; MGI: 1855688; HomoloGene: 38178; GeneCards: VTI1B; OMA:VTI1B - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	67,674,820 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	79,219,441 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; amygdala; ; anterior cingulate cortex; ; nucleus accumbens; ; prefrontal cortex; ; right frontal lobe; ; putamen; ; caudate nucleus; ; hypothalamus; ; optic nerve;
	Top expressed in
	dorsal striatum; ; globus pallidus; ; olfactory tubercle; ; amygdala; ; nucleus accumbens; ; transitional epithelium of urinary bladder; ; cingulate gyrus; ; arcuate nucleus; ; prefrontal cortex; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SNAP receptor activity; protein binding; chloride channel inhibitor activity; SNARE binding;
Cellular component	integral component of membrane; recycling endosome; vesicle; endosome; Golgi apparatus; intracellular membrane-bounded organelle; late endosome membrane; synaptic vesicle; membrane; lysosomal membrane; neuronal cell body; perinuclear region of cytoplasm; lysosome; ER to Golgi transport vesicle membrane; SNARE complex; endoplasmic reticulum membrane; extracellular region; cytosol; platelet alpha granule lumen; early endosome membrane; recycling endosome membrane;
Biological process	membrane fusion; vesicle docking involved in exocytosis; autophagosome maturation; protein transport; cell population proliferation; intracellular protein transport; vesicle-mediated transport; regulation of protein localization to plasma membrane; Golgi to vacuole transport; vesicle fusion with Golgi apparatus; endoplasmic reticulum to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; protein targeting to vacuole; retrograde transport, endosome to Golgi; platelet degranulation;
	Sources:Amigo / QuickGO
Orthologs
	10490
	53612
	ENSG00000100568
	ENSMUSG00000021124
	Q9UEU0
	O88384
	NM_006370
	NM_016800; NM_001364374
	NP_006361
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicle transport through interaction with t-SNAREs homolog 1B is a protein that in humans is encoded by the VTI1B gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100568 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021124 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Li HC, Tahara H, Tsuyama N, Ide T (July 1998). "A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts". Biochem Biophys Res Commun. 247 (1): 70–4. doi:10.1006/bbrc.1998.8737. PMID 9636656.
^ Fischer von Mollard G, Stevens TH (February 1998). "A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways". J Biol Chem. 273 (5): 2624–30. doi:10.1074/jbc.273.5.2624. PMID 9446565.
^ "Entrez Gene: VTI1B vesicle transport through interaction with t-SNAREs homolog 1B (yeast)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000100568 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021124 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9636656-5] Li HC, Tahara H, Tsuyama N, Ide T (July 1998). "A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts". Biochem Biophys Res Commun. 247 (1): 70–4. doi:10.1006/bbrc.1998.8737. PMID 9636656.

[pmid9446565-6] Fischer von Mollard G, Stevens TH (February 1998). "A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways". J Biol Chem. 273 (5): 2624–30. doi:10.1074/jbc.273.5.2624. PMID 9446565.

[entrez-7] "Entrez Gene: VTI1B vesicle transport through interaction with t-SNAREs homolog 1B (yeast)".

VTI1B information

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