VPS28 information

VPS28
Identifiers
Aliases	VPS28, ESCRT-I subunit, VPS28 subunit of ESCRT-I
External IDs	OMIM: 611952; MGI: 1914164; HomoloGene: 69205; GeneCards: VPS28; OMA:VPS28 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	144,428,563 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	76,510,286 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; left testis; ; apex of heart; ; right lobe of thyroid gland; ; right ovary; ; left ovary; ; duodenum; ; fundus; ; right testis; ; left lobe of thyroid gland;
	Top expressed in
	ankle joint; ; facial motor nucleus; ; right lung lobe; ; central gray substance of midbrain; ; vestibular membrane of cochlear duct; ; anterior horn of spinal cord; ; transitional epithelium of urinary bladder; ; nucleus of stria terminalis; ; granulocyte; ; adrenal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-containing complex binding; ubiquitin binding; protein binding;
Cellular component	cytoplasm; cytosol; endosome; membrane; late endosome membrane; plasma membrane; early endosome; endosome membrane; extracellular exosome; ESCRT I complex; host cell;
Biological process	intracellular transport of virus; positive regulation of ubiquitin-dependent endocytosis; positive regulation of protein catabolic process; viral budding via host ESCRT complex; viral life cycle; multivesicular body assembly; endosomal transport; negative regulation of protein ubiquitination; protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; macroautophagy; transport; endosome transport via multivesicular body sorting pathway;
	Sources:Amigo / QuickGO
Orthologs
	51160
	66914
	ENSG00000160948; ENSG00000285339
	ENSMUSG00000115987
	Q9UK41; Q548N1
	Q9D1C8
	NM_016208; NM_183057
	NM_025842; NM_001305668
	NP_057292; NP_898880; NP_057292.1
	NP_001292597; NP_080118
	Wikidata
View/Edit Human	View/Edit Mouse

Vacuolar protein sorting-associated protein 28 homolog is a protein that in humans is encoded by the VPS28 gene.^[5]

^ ^a ^b ^c ENSG00000285339 GRCh38: Ensembl release 89: ENSG00000160948, ENSG00000285339 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000115987 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)".

[refGRCh38Ensembl-1] ENSG00000285339 GRCh38: Ensembl release 89: ENSG00000160948, ENSG00000285339 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000115987 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)".

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