VPS24 information

CHMP3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XZE, 3FRT, 3FRV, 2GD5
Identifiers
Aliases	CHMP3, NEDF, VPS24, CGI-149, charged multivesicular body protein 3
External IDs	OMIM: 610052; MGI: 1913950; HomoloGene: 6368; GeneCards: CHMP3; OMA:CHMP3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	86,563,479 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	71,559,593 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; secondary oocyte; ; cerebellar vermis; ; nipple; ; skin of hip; ; urethra; ; saphenous vein; ; parotid gland; ; rectum; ; trabecular bone;
	Top expressed in
	granulocyte; ; dentate gyrus of hippocampal formation granule cell; ; seminal vesicula; ; neural layer of retina; ; superior frontal gyrus; ; right kidney; ; spermatocyte; ; lip; ; muscle of thigh; ; esophagus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; phosphatidylcholine binding; protein homodimerization activity; ubiquitin-specific protease binding; identical protein binding;
Cellular component	cytoplasm; membrane; plasma membrane; endosome; late endosome membrane; extracellular exosome; ESCRT III complex; cytosol; intracellular anatomical structure; late endosome; cytoplasmic vesicle; multivesicular body;
Biological process	autophagosome maturation; viral life cycle; protein polymerization; multivesicular body assembly; cell cycle; cell division; regulation of mitotic spindle assembly; endosomal transport; regulation of centrosome duplication; apoptotic process; protein heterooligomerization; vacuolar transport; septum digestion after cytokinesis; protein transport; nucleus organization; mitotic metaphase plate congression; multivesicular body sorting pathway; regulation of exosomal secretion; macroautophagy; multivesicular body-lysosome fusion; regulation of early endosome to late endosome transport; transport; viral budding via host ESCRT complex; endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; midbody abscission;
	Sources:Amigo / QuickGO
Orthologs
	51652
	66700
	ENSG00000115561
	ENSMUSG00000053119
	Q9Y3E7
	Q9CQ10
	NM_001005753; NM_001193517; NM_016079
	NM_025783; NM_001355674; NM_001355675; NM_001361405
	NP_001005753; NP_001180446; NP_057163
	NP_080059; NP_001342603; NP_001342604; NP_001348334
	Wikidata
View/Edit Human	View/Edit Mouse

Charged multivesicular body protein 3 is a protein that in humans is encoded by the VPS24 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000115561 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000053119 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wilson EM, Oh Y, Hwa V, Rosenfeld RG (Sep 2001). "Interaction of IGF-binding protein-related protein 1 with a novel protein, neuroendocrine differentiation factor, results in neuroendocrine differentiation of prostate cancer cells". J Clin Endocrinol Metab. 86 (9): 4504–11. doi:10.1210/jcem.86.9.7845. PMID 11549700.
^ Whitley P, Reaves BJ, Hashimoto M, Riley AM, Potter BV, Holman GD (Sep 2003). "Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization". J Biol Chem. 278 (40): 38786–95. doi:10.1074/jbc.M306864200. PMID 12878588.
^ "Entrez Gene: VPS24 vacuolar protein sorting 24 homolog (S. cerevisiae)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000115561 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000053119 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11549700-5] Wilson EM, Oh Y, Hwa V, Rosenfeld RG (Sep 2001). "Interaction of IGF-binding protein-related protein 1 with a novel protein, neuroendocrine differentiation factor, results in neuroendocrine differentiation of prostate cancer cells". J Clin Endocrinol Metab. 86 (9): 4504–11. doi:10.1210/jcem.86.9.7845. PMID 11549700.

[pmid12878588-6] Whitley P, Reaves BJ, Hashimoto M, Riley AM, Potter BV, Holman GD (Sep 2003). "Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization". J Biol Chem. 278 (40): 38786–95. doi:10.1074/jbc.M306864200. PMID 12878588.

[entrez-7] "Entrez Gene: VPS24 vacuolar protein sorting 24 homolog (S. cerevisiae)".

VPS24 information

and 3 Related for: VPS24 information

VPS24

ESCRT

IGFBP7