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Coronary vasospasm information


Coronary vasospasm refers to when a coronary artery suddenly undergoes either complete or sub-total temporary occlusion.[1]

In 1959, Prinzmetal et al. described a type of chest pain resulting from coronary vasospasm, referring to it as a variant form of classical angina pectoris.[2] Consequently, this angina has come to be reported and referred to in the literature as Prinzmetal angina.[3] A subsequent study distinguished this type of angina from classical angina pectoris further by showing normal coronary arteries on cardiac catheterization. This finding is unlike the typical findings in classical angina pectoris, which usually shows atherosclerotic plaques on cardiac catheterization.[3]

When coronary vasospasm occurs, the occlusion temporarily produces ischemia. A wide array of symptoms or presentations can follow: ranging from asymptomatic myocardial ischemia, sometimes referred to as silent ischemia, to myocardial infarction and even sudden cardiac death.[4][1]

  1. ^ a b Hung, Ming-Jui; Hu, Patrick; Hung, Ming-Yow (2014). "Coronary Artery Spasm: Review and Update". International Journal of Medical Sciences. 11 (11): 1161–1171. doi:10.7150/ijms.9623. ISSN 1449-1907. PMC 4166862. PMID 25249785.
  2. ^ Prinzmetal, Myron; Kennamer, Rexford; Merliss, Reuben; Wada, Takashi; Bor, Naci (September 1959). "Angina pectoris I. A variant form of angina pectoris". The American Journal of Medicine. 27 (3): 375–388. doi:10.1016/0002-9343(59)90003-8. ISSN 0002-9343. PMID 14434946.
  3. ^ a b Cheng, Tsung O. (1972-05-01). "Variant Angina of Printzmetal with Normal Coronary Arteriograms: A Variant of the Variant". Annals of Internal Medicine. 76 (5): 862. doi:10.7326/0003-4819-76-5-862_2. ISSN 0003-4819.
  4. ^ Robert, Chahine (1984). "Coronary Artery Spasm". JAMA: The Journal of the American Medical Association. 251 (8): 1097. doi:10.1001/JAMA.1984.03340320073040. S2CID 72379696.

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