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Ultracentrifuge information


A standard ultracentrifuge by manufacturer Beckman Coulter

An ultracentrifuge is a centrifuge optimized for spinning a rotor at very high speeds, capable of generating acceleration as high as 1 000 000 g (approx. 9 800 km/s²).[1] There are two kinds of ultracentrifuges, the preparative and the analytical ultracentrifuge. Both classes of instruments find important uses in molecular biology, biochemistry, and polymer science.[2]

  1. ^ "Optima MAX-XP". Retrieved 2016-02-20.
  2. ^ Susan R. Mikkelsen & Eduardo Cortón. Bioanalytical Chemistry, Ch. 13. Centrifugation Methods. John Wiley & Sons, Mar 4, 2004, pp. 247-267.

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Ultracentrifuge

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An ultracentrifuge is a centrifuge optimized for spinning a rotor at very high speeds, capable of generating acceleration as high as 1 000 000 g (approx...

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Svedberg

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for his work on disperse systems, colloids and his invention of the ultracentrifuge. The Svedberg coefficient is a nonlinear function. A particle's mass...

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Instruments used in medical laboratories

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light microscope Gel electrophoresis apparatus High-speed centrifuge Ultracentrifuge Gaschromatograph Practical Pathology by Dr. P. Chakraborty and Dr....

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Sedimentation coefficient

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centrifuge (typically in multiples of tens of thousands of gravities in an ultracentrifuge) is balanced by the viscous resistance (or "drag") of the fluid (normally...

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Theodor Svedberg

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Nobel laureate for his research on colloids and proteins using the ultracentrifuge. Svedberg was active at Uppsala University from the mid-1900s to late...

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Differential centrifugation

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organelles: The lysed sample is now ready for centrifugation in an ultracentrifuge. An ultracentrifuge consists of a refrigerated, low-pressure chamber containing...

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Analytical ultracentrifugation

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analytical technique which combines an ultracentrifuge with optical monitoring systems. In an analytical ultracentrifuge (commonly abbreviated as AUC), a sample’s...

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Centrifugation

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use preparative ultracentrifuges if they need the flexibility to change the type of rotor in the instrument. Preparative ultracentrifuges can be equipped...

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Beckman Coulter

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the Apollo Guidance Computer. In 1954, Beckman Instruments acquired ultracentrifuge maker Spinco (Specialized Instruments Corp.). The Spinco division went...

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Sedimentation equilibrium

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the particles will sediment. Modern applications use the analytical ultracentrifuge. The theoretical basis for the measurements is developed from the Mason-Weaver...

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Centrifuge

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cream separator found in dairies. Very high speed centrifuges and ultracentrifuges able to provide very high accelerations can separate fine particles...

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Lipid profile

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lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge". Clin. Chem. 18 (6): 499–502. doi:10.1093/clinchem/18.6.499. PMID 4337382;...

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Sedimentation

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where the force of gravity is augmented with centrifugal force in an ultracentrifuge. The physical process of sedimentation (the act of depositing sediment)...

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5S ribosomal RNA

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designation 5S refers to the molecule's sedimentation velocity in an ultracentrifuge, which is measured in Svedberg units (S). In prokaryotes, the 5S rRNA...

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Jesse Beams

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During World War II, he worked on the Manhattan Project, where his ultracentrifuge was used to demonstrate the separation of the lighter uranium isotope...

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Laboratory centrifuge

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big footprint) Ultracentrifuges (analytical and preparative models) Because of the heat generated by air friction (even in ultracentrifuges, where the rotor...

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List of inventors

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Surgery, Rhinoplasty Theodor Svedberg (1884–1971), Sweden – Analytical ultracentrifuge Joseph Swan (1828–1914), UK – Incandescent light bulb Robert Swanson...

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AMOLF

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did ultracentrifuge concepts, cathode dispersion, excitation of gases by using energetic ions and research on molecular beams. The gas-ultracentrifuge developed...

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Pathophysiology

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gap between cytology and biochemistry by applying new technology —ultracentrifuge and electron microscope— to identify and deconstruct cell structures...

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Gernot Zippe

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(צנטריפוגה). "The problem of Uranium Isotope Separation by Means of Ultracentrifuge in the USSR" (PDF). Central Intelligence Agency. 1957-10-08. Retrieved...

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Hypercholesterolemia

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lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge". Clinical Chemistry. 18 (6): 499–502. doi:10.1093/clinchem/18.6.499...

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Khan Research Laboratories

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control (CNC) from China to provide machining of the high-strength ultracentrifuges which was able to produce the uranium hexafluoride (UF6) gas that the...

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Ghulam Dastagir Alam

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College University Punjab University University College London Known for Ultracentrifuge development Quantum Mechanics Ion Scattering Published work in Calculus...

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Gas centrifuge

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developed the process by separating two chlorine isotopes through a vacuum ultracentrifuge. It was one of the initial isotopic separation means pursued during...

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Globular protein

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determined without the means of modern techniques, but only by using ultracentrifuges or dynamic light scattering techniques. The spherical structure is...

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