UBE2E1 information

UBE2E1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XR9, 3BZH, 4JJQ
Identifiers
Aliases	UBE2E1, UBCH6, ubiquitin conjugating enzyme E2 E1
External IDs	OMIM: 602916; MGI: 107411; HomoloGene: 84372; GeneCards: UBE2E1; OMA:UBE2E1 - orthologs
EC number	2.3.2.24
Gene location (Human)
Chr.	Chromosome 3 (human)
End	23,891,640 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	4,186,974 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; oral cavity; ; ventricular zone; ; embryo; ; skin of arm; ; superficial temporal artery; ; bronchial epithelial cell; ; mucosa of paranasal sinus; ; pons; ; lower lobe of lung;
	Top expressed in
	otic placode; ; otic vesicle; ; saccule; ; mammillary body; ; ventral tegmental area; ; dorsomedial hypothalamic nucleus; ; arcuate nucleus; ; paraventricular nucleus of hypothalamus; ; nasal epithelium; ; olfactory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; ISG15 transferase activity; ubiquitin-protein transferase activity; protein binding; ATP binding; ubiquitin conjugating enzyme activity;
Cellular component	cytosol; ubiquitin ligase complex; nucleoplasm; nucleus;
Biological process	histone monoubiquitination; ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein K48-linked ubiquitination; ISG15-protein conjugation; anaphase-promoting complex-dependent catabolic process; histone H2B ubiquitination; protein ubiquitination; regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	7324
	22194
	ENSG00000170142
	ENSMUSG00000021774
	P51965
	P52482
	NM_001202476; NM_003341; NM_182666
	NM_009455
	NP_001189405; NP_003332; NP_872607; NP_003332.1
	NP_033481
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-conjugating enzyme E2 E1 is a protein that in humans is encoded by the UBE2E1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170142 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021774 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nuber U, Schwarz S, Kaiser P, Schneider R, Scheffner M (Mar 1996). "Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5". J. Biol. Chem. 271 (5): 2795–800. doi:10.1074/jbc.271.5.2795. PMID 8576257.
^ "Entrez Gene: UBE2E1 ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170142 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021774 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8576257-5] Nuber U, Schwarz S, Kaiser P, Schneider R, Scheffner M (Mar 1996). "Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5". J. Biol. Chem. 271 (5): 2795–800. doi:10.1074/jbc.271.5.2795. PMID 8576257.

[entrez-6] "Entrez Gene: UBE2E1 ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)".

UBE2E1 information

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UBE2E1

Housekeeping gene

Ring finger protein 167

Ataxin 1

RNF8