Global InformationTylonycteris bat coronavirus HKU4 information
| Tylonycteris bat coronavirus HKU4 | |
|---|---|
Virus classification 
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| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | Merbecovirus |
| Species: | Tylonycteris bat coronavirus HKU4
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Tylonycteris bat coronavirus HKU4 (Bat-CoV HKU4) is an enveloped, positive-sense single-stranded RNA virus mammalian Group 2 Betacoronavirus that has been found to be genetically related to the Middle East respiratory syndrome-related coronavirus (MERS-CoV) that is responsible for the 2012 Middle East respiratory syndrome coronavirus outbreak in Saudi Arabia, Jordan, United Arab Emirates, the United Kingdom, France, and Italy.[1][2][3][4]
- ^ Woo, Patrick CY; Lau, Susanna KP; Li, Kenneth SM; Tsang, Alan KL; Yuen, Kwok-Yung (2012). "Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5". Emerging Microbes & Infections. 1 (11): e35–. doi:10.1038/emi.2012.45. PMC 3630921. PMID 26038405.
- ^ Zaki, Ali M.; Van Boheemen, Sander; Bestebroer, Theo M.; Osterhaus, Albert D.M.E.; Fouchier, Ron A.M. (2012). "Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia". New England Journal of Medicine. 367 (19): 1814–20. doi:10.1056/NEJMoa1211721. PMID 23075143.
- ^ Woo, Patrick C.Y.; Lau, Susanna K.P.; Li, Kenneth S.M.; Poon, Rosana W.S.; Wong, Beatrice H.L.; Tsoi, Hoi-wah; Yip, Bethanie C.K.; Huang, Yi; Chan, Kwok-Hung; Yuen, Kwok-Yung (2006). "Molecular diversity of coronaviruses in bats". Virology. 351 (1): 180–7. doi:10.1016/j.virol.2006.02.041. PMC 7111821. PMID 16647731.
- ^ Lau, S. K. P.; Li, K. S. M.; Tsang, A. K. L.; Lam, C. S. F.; Ahmed, S.; Chen, H.; Chan, K.-H.; Woo, P. C. Y.; Yuen, K.-Y. (2013). "Genetic characterization of betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of Pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: Implications for the origin of the novel Middle East respiratory syndrome coronavirus". Journal of Virology. 87 (15): 8638–50. doi:10.1128/JVI.01055-13. PMC 3719811. PMID 23720729.