Troxerutin is a flavonol, a type of flavonoid, derived from rutin.[1] It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the Japanese pagoda tree.
It is used as a vasoprotective.[2]
Troxerutin has been shown in mice to reverse CNS insulin resistance and reduce reactive oxygen species induced by a high-cholesterol diet.[3]
^Zhang ZF, Fan SH, Zheng YL, Lu J, Wu DM, Shan Q, Hu B (September 2014). "Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice". Biochemical Pharmacology. 91 (1): 74–86. doi:10.1016/j.bcp.2014.07.002. PMID 25026599.
^Riccioni C, Sarcinella R, Izzo A, Palermo G, Liguori M (February 2004). "[Effectiveness of Troxerutin in association with Pycnogenol in the pharmacological treatment of venous insufficiency]". Minerva Cardioangiologica. 52 (1): 43–8. PMID 14765037.
^Lu J, Wu DM, Zheng ZH, Zheng YL, Hu B, Zhang ZF (March 2011). "Troxerutin protects against high cholesterol-induced cognitive deficits in mice". Brain. 134 (Pt 3): 783–97. doi:10.1093/brain/awq376. PMID 21252113.
Troxerutin is a flavonol, a type of flavonoid, derived from rutin. It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica...
severity of possible side effects remains to be fairly inconclusive. With troxerutin, it has been investigated for use in the treatment of hemorrhoids. Capillary...
derivatives of rutosides. Examples include: Monoxerutin Dihydroxyethylrutoside Troxerutin Tetrahydroxyethylrutoside Oxerutins are semisynthetic derivatives of plant...