Chemical structures of selected examples of triazolopyridine isomers and their IUPAC names
Triazolopyridines are a class of heterocyclic chemical compounds with a triazole ring fused to a pyridine ring. There are multiple isomers which differ by the location of the nitrogen atoms and the nature of the ring fusion.
The term triazolopyridine can also refer to a class of antidepressant drugs whose chemical structure includes a trazolopyridine-derived ring system.[1] One example is trazodone.[2]
Other pharmaceutical drugs that contain a triazolopyridine ring system include filgotinib, tucatinib, and enarodustat. In addition, the reagents used in organic chemistry HATU, HOAt, and PyAOP[3] are triazolopyridine derivatives.
Triazolopyridines are a class of heterocyclic chemical compounds with a triazole ring fused to a pyridine ring. There are multiple isomers which differ...
to: Purine Purine analogues 5-Aza-7-deazapurine Pyridine analogues Triazolopyridine 4-azidopyridine This set index page lists chemical structure articles...
sulfated similarly to other trazodone metabolites. Trazodone is a triazolopyridine derivative and a phenylpiperazine that is structurally related to nefazodone...
HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic...
Tucatinib, sold under the brand name Tukysa, is an anticancer medication used for the treatment of HER2-positive breast cancer. It is a small molecule...
Filgotinib, sold under the brand name Jyseleca, is a medication used for the treatment of rheumatoid arthritis (RA). It was developed by the Belgian-Dutch...
2020). "Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase"...
PyAOP ((7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate) is a coupling reagent used in solid phase peptide synthesis. It is a derivative...
Enarodustat (development code JTZ-951; brand name Enaroy) is a drug used for the treatment of anemia, especially when associated with chronic kidney disease...
Lotrifen (INNTooltip International Nonproprietary Name), also known as trazisoquine and sold under the brand names Canocenta and Privaprol, is an abortifacient...
Dapiprazole (brand name Rev-Eyes) is an alpha-1 blocker. It is used to reverse mydriasis after eye examination. Doughty MJ, Lyle WM (May 1992). "A review...
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