For the New Zealand cricketer, see Tom Blundell (cricketer).
British biochemist
Sir Tom Blundell
FRS FRSC FMedSci FRSB MAE
Blundell in 2006
Born
Thomas Leon Blundell
(1942-07-07) 7 July 1942 (age 81)[8]
Brighton, England, UK
Education
Steyning Grammar School
Alma mater
University of Oxford (BA, DPhil)[8]
Known for
Astex
Insulin structure[9]
Drug design
Spouse
Lady Bancinyane Lynn Sibanda
(m. 1987)
[8]
Children
3[10]
Awards
Knight Bachelor (1997)
EMBO Member (1986)[1]
Honorary Doctorates from 16 universities[citation needed]
Scientific career
Fields
Structural biology[2]
Bioinformatics[2]
Biochemistry[2]
Drug Discovery[2]
Institutions
University of Cambridge
University of Oxford
University of Sussex
Birkbeck, University of London
Biotechnology and Biological Sciences Research Council
Agricultural and Food Research Council
Astex
Thesis
The determination by X-ray diffraction methods of the crystal and molecular structures of some co-ordination compounds(1969)
Doctoral advisor
Herbert M Powell[3]
Doctoral students
Tim Hubbard[4]
Laurence Pearl[5]
Andrej Šali[6]
Charlotte Deane[7]
Website
www.bioc.cam.ac.uk/research/blundell
Sir Thomas Leon Blundell, FRS FRSC FMedSci MAE (born 7 July 1942) is a British biochemist, structural biologist, and science administrator. He was a member of the team of Dorothy Hodgkin that solved in 1969 the first structure of a protein hormone, insulin. Blundell has made contributions to the structural biology of polypeptide hormones, growth factors, receptor activation, signal transduction, and DNA double-strand break repair, subjects important in cancer, tuberculosis, and familial diseases.[11] He has developed software for protein modelling and understanding the effects of mutations on protein function, leading to new approaches to structure-guided and Fragment-based lead discovery. In 1999 he co-founded the oncology company Astex Therapeutics, which has moved ten drugs into clinical trials. Blundell has played central roles in restructuring British research councils and, as President of the UK Science Council, in developing professionalism in the practice of science.[12]
^Anon (1996). "Tom L. Blundell". people.embo.org. Heidelberg: European Molecular Biology Organization.
^ abcdCite error: The named reference gs was invoked but never defined (see the help page).
^Cite error: The named reference bdphil was invoked but never defined (see the help page).
^Hubbard, Timothy John Philip (1988). The design, expression and characterisation of a novel protein. london.ac.uk (PhD thesis). University of London. OCLC 940320228. Copac 29528696.
^Sali, Andrej (1991). Modelling three-dimensional structure of a protein from its amino acid sequence. london.ac.uk (PhD thesis). London, Birkbeck College. OCLC 500526292. EThOS uk.bl.ethos.415316.
^Deane, Charlotte (2000). Protein structure prediction: amino acid propensities and comparative modelling (PhD thesis). EThOS uk.bl.ethos.598479.
^ abcAnon (2015). "Blundell, Sir Thomas Leon, (Sir Tom)". Who's Who (online Oxford University Press ed.). A & C Black. doi:10.1093/ww/9780199540884.013.U7914. (Subscription or UK public library membership required.)
^Cambridge, University of (29 March 2018). "The multi-talented scientist who finds inspiration in far-flung places". Medium.com. Retrieved 3 July 2018.
^Tom Blundell publications indexed by the Scopus bibliographic database. (subscription required)
^"Professor Sir Tom Blundell FRS FMedSci". British Humanist Association. Retrieved 22 March 2014.
Sir Thomas Leon Blundell, FRS FRSC FMedSci MAE (born 7 July 1942) is a British biochemist, structural biologist, and science administrator. He was a member...
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Mark Blundell (born 8 April 1966) is a British racing driver who competed in Formula One for four seasons, sports cars, and CART. He won the 1992 24 Hours...
the International Cricket Council (ICC). Two cricketers, New Zealand's TomBlundell and Bangladesh's Abu Jayed, had not played in a One Day International...
were ruled out of the series due to their respective injuries, with TomBlundell and Zak Foulkes were named as their replacements. On 20 April 2024, Pakistan's...
prominently used in the Weepul promotional toys, invented in the 1970s by TomBlundell, an executive of the toy company BIPO, who stuck googly eyes to a small...
(1943-1949) Frank George Young (1949-1975) Hans Kornberg (1975-1995) TomBlundell (1995-2009) Gerard Evan (2009-2022) Laura Machesky (2022- ) "Professors"...
themselves now train future leaders across the world. Together with TomBlundell, she wrote an influential textbook on protein crystallography. She was...
include Sir David Attenborough, Martin Hume Johnson, Jasmin Fisher, Sir TomBlundell and Dame Nancy Rothwell. See the Category: Fellows of the Royal Society...
Princeton University Press. p. 289. ISBN 978-1-4008-3532-4. Lancaster, Tom; Blundell, Stephen J. (2014-04-17), "Statistical field theory", Quantum Field...
Brendon Kuruppu, Romesh Kaluwitharana, England's Matt Prior, New Zealand's TomBlundell and England's Ben Foakes all scored centuries on their debuts in their...
University of Cambridge to study structural bioinformatics supervised by TomBlundell. In 2000 she published her thesis entitled "Protein structure prediction:...
Bibcode:1930RSPSA.126..360D. doi:10.1098/rspa.1930.0013. Lancaster, Tom; Blundell, Stephen J.; Blundell, Stephen (2014). Quantum Field Theory for the Gifted Amateur...
from the original on 31 March 2019. Retrieved 15 April 2019. "Uncapped Blundell named in New Zealand World Cup squad, Sodhi preferred to Astle". International...
diseases of the central nervous system. Astex was founded in 1999 by Sir TomBlundell, Chris Abell & Harren Jhoti, and is located in Cambridge, England. Astex...
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