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Tin mesoporphyrin information


Tin mesoporphyrin
Names
IUPAC name
3-[18-(2-carboxyethyl)-8,13-diethyl-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;tin(4+);dichloride
Identifiers
CAS Number
  • 106344-20-1
3D model (JSmol)
  • Interactive image
DrugBank
  • DB04912
PubChem CID
  • 15978579
UNII
  • 0KAE1U0G7Q
InChI
  • InChI=1S/C34H38N4O4.2ClH.Sn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;;/h13-16H,7-12H2,1-6H3,(H4,35,36,37,38,39,40,41,42);2*1H;/q;;;+4/p-4
    Key: LLDZJTIZVZFNCM-UHFFFAOYSA-J
SMILES
  • CCC1=C(C2=NC1=CC3=C(C(=C([N-]3)C=C4C(=C(C(=CC5=NC(=C2)C(=C5C)CC)[N-]4)C)CCC(=O)O)CCC(=O)O)C)C.[Cl-].[Cl-].[Sn+4]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tin mesoporphyrin (SnMP), also known as stannsoporfin, is a synthetic metalloporphyrin,[1] which consists of a group of competitive inhibitors of heme oxygenase, a rate-limiting enzyme in the heme catabolic pathway.[2] Tin mesoporphyrin is one of the more potent metalloporphyrin compound out of all the others.

  1. ^ "Mesoporphyrin".
  2. ^ "Stannsoporfin".

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Tin mesoporphyrin

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Tin mesoporphyrin (SnMP), also known as stannsoporfin, is a synthetic metalloporphyrin, which consists of a group of competitive inhibitors of heme oxygenase...

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Porphyria

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should be treated with the addition of hematin, heme arginate, or even tin mesoporphyrin, as these are signs of impending syndrome of inappropriate antidiuretic...

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Neonatal jaundice

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the 1970s in hyperbilirubinemia due to ABO hemolytic disease. While tin mesoporphyrin IX may decrease bilirubin such use is not recommended in babies. Preclinical...

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