Pharmacological test used to diagnose myasthenia gravis
Tensilon test
Reversal of ptosis following tensilon test in a myasthenia gravis
Synonyms
Edrophonium test
Purpose
Diagnose neural diseases
MedlinePlus
003930
A tensilon test, also called an edrophonium test, is a pharmacological test used for the diagnosis of certain neural diseases, especially myasthenia gravis.[1] It is also used to distinguish a myasthenic crisis from a cholinergic crisis in individuals undergoing treatment for myasthenia gravis. The test has fallen out of use due to suboptimal sensitivity and specificity as well as associated adverse risks.[2] Edrophonium is no longer available in the United States and many other countries as of 2018.[2]
^Pascuzzi, Robert M. (March 2003). "The edrophonium test". Seminars in Neurology. 23 (1): 83–88. doi:10.1055/s-2003-40755. ISSN 0271-8235. PMID 12870109.
^ ab"Diagnosis of myasthenia gravis". UpToDate. Retrieved 2023-07-11.
A tensilontest, also called an edrophonium test, is a pharmacological test used for the diagnosis of certain neural diseases, especially myasthenia gravis...
sold under the trade names Tensilon and Enlon (according to FDA Orange Book). Edrophonium (by the so-called Tensilontest) is used to differentiate myasthenia...
after tensilontest. This test is less sensitive than anti-AChR antibody titers and electromyography, and hence is used only as a screening test in clinical...
conduction test (electromyography, or EMG), and an edrophonium chloride (Tensilon) test for myasthenia gravis. A definite diagnosis can be made if botulinum...
the day (with increasing extraocular muscle fatigue). A tensilon (edrophonium chloride) test can be used, which temporarily blocks the breakdown of acetylcholine...
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