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Targeted lung denervation information


Targeted lung denervation
SpecialtyPulmonology
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Targeted lung denervation (TLD) is a procedure, that is currently being studied, to try to improve chronic obstructive pulmonary disease (COPD).[1] Evidence to support its use is insufficient as of 2015.[1] TLD is intended to block airway nerves of the parasympathetic nervous system to try to relax the airways.[2] The procedure is done using a balloon catheter through a bronchoscope and uses radio frequency energy. The bronchoscope is passed through the person's mouth and into their lungs. A dual-cooled radiofrequency ablation catheter is passed through the bronchoscope to provide the treatment.

  1. ^ a b Gompelmann D, Eberhardt R, Herth FJ (August 2015). "Novel Endoscopic Approaches to Treating Chronic Obstructive Pulmonary Disease and Emphysema". Seminars in Respiratory and Critical Care Medicine. 36 (4): 609–15. doi:10.1055/s-0035-1555614. PMID 26238645. S2CID 9279526.
  2. ^ Belmont, Kristen E. (Nov 1, 2005). "Cholinergic Pathways in the Lungs and Anticholinergic Therapy for Chronic Obstructive Pulmonary Disease". Proceedings of the American Thoracic Society. 2 (4): 297–304. doi:10.1513/pats.200504-043SR. PMID 16267352.

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Targeted lung denervation

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the aim of reducing renal sympathetic overactivity (so-called "renal denervation") and thereby reduce blood pressure. It has been employed in clinical...

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noninvasive, negative-pressure ventilator, more commonly called an iron lung, was used to artificially maintain respiration during an acute polio infection...

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protect against the susceptibility to convulsion, drug sensitization, denervation supersensitivity, ischemic lesions and stress. It has also been suggested...

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a lack of good quality evidence to support the use of radiofrequency denervation for pain relief. KT Tape has been found to be no different for management...

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neurons for neural input, now have decreased innervation (also called denervation), and therefore have decreased input from the central nervous system...

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