Protein-coding gene in the species Homo sapiens
TDRD7 Available structures PDB Ortholog search: PDBe RCSB
Identifiers Aliases TDRD7 , CATC4, CTRCT36, PCTAIRE2BP, TRAP, tudor domain containing 7External IDs OMIM: 611258; MGI: 2140279; HomoloGene: 8618; GeneCards: TDRD7; OMA:TDRD7 - orthologs Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q22.33 Start 97,412,096 bp[1] End 97,496,125 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 B1 Start 45,965,334 bp[2] End 46,034,761 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte jejunal mucosa retinal pigment epithelium internal globus pallidus sperm pars reticulata monocyte duodenum testicle middle frontal gyrus
Top expressed in epithelium of lens spermatid neural layer of retina seminiferous tubule spermatocyte retinal pigment epithelium granulocyte mucous cell of stomach intestinal villus jejunum
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
mRNA binding
protein binding
protein N-terminus binding
RNA binding
Cellular component
cytoplasm
chromatoid body
mitochondrial matrix
ribonucleoprotein granule
Biological process
posttranscriptional regulation of gene expression
cell differentiation
lens fiber cell differentiation
lens morphogenesis in camera-type eye
spermatogenesis
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_001290475 NM_146142 NM_001355189
RefSeq (protein) NP_001277404 NP_666254 NP_001342118
Location (UCSC) Chr 9: 97.41 – 97.5 Mb Chr 4: 45.97 – 46.03 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Tudor domain-containing protein 7 is a protein that in humans is encoded by the TDRD7 gene.[5] [6]
In melanocytic cells TDRD7 gene expression may be regulated by MITF.[7]
^ a b c GRCh38: Ensembl release 89: ENSG00000196116 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035517 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
^ "Entrez Gene: TDRD7 tudor domain containing 7".
^ Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, Valgeirsdottir S, Bergsteinsdottir K, Schepsky A, Dummer R, Steingrimsson E (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res . 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x . PMID 19067971. S2CID 24698373.
Last Update: 2024-01-15T11:00:16Z
the TDRD7 gene. In melanocytic cells TDRD7 gene expression may be regulated by MITF. Various single nucleotide polymorphisms (SNPs) of the TDRD7 gene...
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Last Update: 2024-06-09T04:52:47Z
subunit alpha TDRD3 Tudor Domain Containing 3 Tudor Domain Containing 3 TDRD7 Tudor Domain Containing 7 Tudor Domain Containing 7 TERT TERT Telomerase...
Word Count : 12500
Last Update: 2024-06-23T17:12:16Z
including IRF-9, TRIM69, NPIP, TDRD7 , PNPT1 and so on. One of this genes TDRD7 was investigated in more detail. The functional TDRD7 protein inhibits the replication...
Word Count : 31886
Last Update: 2023-01-30T05:21:48Z
functionality is performed both directly through Tudor-containing proteins, such as Tdrd7 , as well as through piRNA synthesis. Tudor domains are essential in the...
Word Count : 1565
Last Update: 2023-12-28T23:34:46Z
with: Aurora A kinase, Aurora B kinase, BARD1, CKAP5, LSM7, SNRPG, and TDRD7 . GRCm38: Ensembl release 89: ENSMUSG00000065954 – Ensembl, May 2017 "Human...
Word Count : 1089