TAF10 information

TAF10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F69, 3M53, 3M54, 3M55, 3M56, 3M57, 3M58, 3M59, 3M5A, 4J7F, 4J7I, 4J83, 4J8O, 4WV4, 5EG2
Identifiers
Aliases	TAF10, TAF2A, TAF2H, TAFII30, TATA-box binding protein associated factor 10
External IDs	OMIM: 600475; MGI: 1346320; HomoloGene: 86923; GeneCards: TAF10; OMA:TAF10 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	6,612,539 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	105,393,568 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right adrenal gland; ; body of pancreas; ; body of stomach; ; right lobe of thyroid gland; ; stromal cell of endometrium; ; right lobe of liver; ; left lobe of thyroid gland; ; right lung; ; left uterine tube;
	Top expressed in
	yolk sac; ; lip; ; superior frontal gyrus; ; interventricular septum; ; spermatocyte; ; spermatid; ; morula; ; thymus; ; proximal tubule; ; neural tube;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; transcription coactivator activity; histone acetyltransferase activity; protein binding; RNA polymerase binding; enzyme binding; estrogen receptor binding; thiol-dependent deubiquitinase; DNA binding; RNA polymerase II general transcription initiation factor activity;
Cellular component	cytoplasm; transcription factor TFTC complex; transcription factor TFIID complex; perinuclear region of cytoplasm; nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; histone deubiquitination; histone H3 acetylation; DNA-templated transcription, initiation; transcription initiation from RNA polymerase II promoter; protein homooligomerization; regulation of signal transduction by p53 class mediator; protein deubiquitination; liver development; apoptotic process; regulation of gene expression; multicellular organism growth; regulation of DNA binding; hepatocyte differentiation; G1/S transition of mitotic cell cycle; positive regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	6881
	24075
	ENSG00000166337
	ENSMUSG00000043866
	Q12962
	Q8K0H5
	NM_006284
	NM_020024
	NP_006275
	NP_064408
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription initiation factor TFIID subunit 10 is a protein that in humans is encoded by the TAF10 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166337 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043866 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jacq X, Brou C, Lutz Y, Davidson I, Chambon P, Tora L (November 1994). "Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor". Cell. 79 (1): 107–17. doi:10.1016/0092-8674(94)90404-9. PMID 7923369. S2CID 19698550.
^ "Entrez Gene: TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166337 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043866 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7923369-5] Jacq X, Brou C, Lutz Y, Davidson I, Chambon P, Tora L (November 1994). "Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor". Cell. 79 (1): 107–17. doi:10.1016/0092-8674(94)90404-9. PMID 7923369. S2CID 19698550.

[entrez-6] "Entrez Gene: TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa".

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