Synthetic rescue (or synthetic recovery or synthetic viability when a lethal phenotype is rescued [1][2]) refers to a genetic interaction in which a cell that is nonviable, sensitive to a specific drug, or otherwise impaired due to the presence of a genetic mutation becomes viable when the original mutation is combined with a second mutation in a different gene.[1] The second mutation can either be a loss-of-function mutation (equivalent to a knockout) or a gain-of-function mutation.[2]
Synthetic rescue could potentially be exploited for gene therapy, but it also provides information on the function of the genes involved in the interaction.
Syntheticrescue (or synthetic recovery or synthetic viability when a lethal phenotype is rescued ) refers to a genetic interaction in which a cell that...
Synthetic lethality is defined as a type of genetic interaction where the combination of two genetic events results in cell death or death of an organism...
phenotypic effects of an already existing mutation in a process defined syntheticrescue. Genetic suppression therefore restores the phenotype seen prior to...
flew with some synthetic kerosene from a non-fossil fuel source. 500 liters of synthetic kerosene was mixed with regular jet fuel. Synthetic kerosene was...
A search-and-rescue (SAR) dog is a dog trained to respond to crime scenes, accidents, missing persons events, as well as natural or man-made disasters...
Synthetic Sin is a 1929 American sound comedy film directed by William A. Seiter, based on a play of the same name. While the film has no audible dialog...
Motter; N. Gulbahce; E. Almaas & A.-L. Barabási (2008). "Predicting syntheticrescues in metabolic networks". Molecular Systems Biology. 4: 1–10. arXiv:0803...
Automatic announcement A synthetic voice announcing an arriving train in Sweden. Problems playing this file? See media help. Speech synthesis is the artificial...
material, but generally is constructed of certain natural or synthetic fibres. Synthetic fibre ropes are significantly stronger than their natural fibre...
alternatives to stainless steel and from circassian walnut stocks to synthetic. This variant of the M77, often known as the Safari Magnum, features a...
Blade Runner and Blade Runner 2049, explore whether or not a constructed, synthetic being should be considered a person. In the films, androids called "replicants"...
types: Clinical LAs: amino amide LAs amino ester LAs Synthetic LAs Cocaine derivatives Synthetic cocaine-derived LAs differ from cocaine because they...
becoming increasingly dangerous due to the increased variety and amount of synthetic household materials Oxygen deficient atmosphere (21% O2 is normal and...
yellow-brown in color, and are generally not re-usable. The more expensive synthetic substitutes are engineered to simulate the ballistic properties of natural...
Westermann, Edward B. (2020). "Old Nazis, Ordinary Men, and New Killers: Synthetic and Divergent Histories of Perpetrators". A Companion to the Holocaust...
is responsible Low-Temperature carbonisation of coal and production of synthetic oil from coal Administration of the Coal Mines (Conservation and Development)...
system activity report, a Unix/Linux performance report utility Search and rescue Nationwide Suspicious Activity Reporting Initiative, US Suspicious activity...
and insulated. The boots can be made of leather, plastic, or modern synthetic materials like Kevlar. The extra height and stiffness of mountaineering...
four-storey high buildings. Construction of support buildings including Typhoon synthetic training facilities and in-flight catering facilities. Demolition of buildings...
skeleton, as compared to other stimulants of the kind. Many of the semi-synthetic cocaine analogues proper which have been made & studied have consisted...
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