Crystal structure of SurE protein from T.maritima in complex with tungstate.
Identifiers
Symbol
SurE
Pfam
PF01975
InterPro
IPR002828
SCOP2
1j9l / SCOPe / SUPFAM
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
In molecular biology, the protein domain surE refers to survival protein E. It was originally found that cells that did not contain this protein, could not survive in the stationary phase, at above normal temperatures, and in high-salt media. Hence the name, survival protein E.[1] It is a metal ion-dependent phosphatase that is found in bacteria, and eukaryotes. It is an important stress response protein.[2] This domain is found in acid phosphatases (EC), 5'-nucleotidases (EC), 3'-nucleotidases (EC) and exopolyphosphatases (EC).
^Li C, Ichikawa JK, Ravetto JJ, Kuo HC, Fu JC, Clarke S (1994). "A new gene involved in stationary-phase survival located at 59 minutes on the Escherichia coli chromosome". J Bacteriol. 176 (19): 6015–22. doi:10.1128/jb.176.19.6015-6022.1994. PMC 196819. PMID 7928962.
^Iwasaki W, Miki K (2007). "Crystal structure of the stationary phase survival protein SurE with metal ion and AMP". J Mol Biol. 371 (1): 123–36. doi:10.1016/j.jmb.2007.05.007. PMID 17561111.
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