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Sulfafurazole information


Not to be confused with sulfadiazine.
Sulfafurazole
Clinical data
AHFS/Drugs.comInternational Drug Names
MedlinePlusa601049
Pregnancy
category
  • To be avoided within two months of term
Routes of
administration		Oral
ATC code
  • J01EB05 (WHO) S01AB02 (WHO) QJ01EQ05 (WHO)
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
ExcretionExcreted unchanged in urine
Identifiers
IUPAC name
  • 4-Amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CAS Number
  • 127-69-5 checkY
PubChem CID
  • 5344
DrugBank
  • DB00263 ☒N
ChemSpider
  • 5151
UNII
  • 740T4C525W
KEGG
  • D00450 checkY
ChEMBL
  • ChEMBL453 ☒N
CompTox Dashboard (EPA)
  • DTXSID6021292 Edit this at Wikidata
ECHA InfoCard100.004.418 Edit this at Wikidata
Chemical and physical data
FormulaC11H13N3O3S
Molar mass267.30 g·mol−1
3D model (JSmol)
  • Interactive image
Melting point194 °C (381 °F)
SMILES
  • CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N
InChI
  • InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3
  • Key:NHUHCSRWZMLRLA-UHFFFAOYSA-N
 ☒NcheckY (what is this?)  (verify)

Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an dimethyl-isoxazole substituent. It possesses antibiotic activity against a wide range of Gram-negative and Gram-positive organisms.[1] It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.

  1. ^ Holmes NE, Grauson ML (October 2017). "Sulfonamides". In Paterson DL, McCarthy JS, Mouton JW, Mills J, Grayson ML, Cosgrove SE, Crowe S, Hope W (eds.). Kucers' The Use of Antibiotics (7th ed.). CRC Press. pp. 1571–1624. ISBN 978-1-4987-4796-7.

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Sulfafurazole

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Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an dimethyl-isoxazole substituent. It possesses antibiotic activity...

Word Count : 124

List of sulfonamides

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in medicine. Short-acting Sulfacetamide Sulfadiazine Sulfadimidine Sulfafurazole (sulfisoxazole) Sulfisomidine (sulfaisodimidine) Sulfaguanidine Intermediate-acting...

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ATC code J01

Last Update:

Sulfamethizole J01EB03 Sulfadimidine J01EB04 Sulfapyridine J01EB05 Sulfafurazole J01EB06 Sulfanilamide J01EB07 Sulfathiazole J01EB08 Sulfathiourea J01EB20...

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C11H13N3O3S

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C11H13N3O3S (molar mass: 267.30 g/mol, exact mass: 267.0678 u) may refer to: Sulfafurazole, or sulfisoxazole Sulfamoxole This set index page lists chemical structure...

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ATC code S01

Last Update:

S01AA32 Bacitracin QS01AA90 Cloxacillin S01AB01 Sulfamethizole S01AB02 Sulfafurazole S01AB03 Sulfadicramide S01AB04 Sulfacetamide S01AB05 Sulfafenazol S01AD01...

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Prontosil

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Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine (Sulfasalazine) Sulfafurazole (Acetyl sulfisoxazole) Sulfanilamide Prontosil Sulfathiazole (Phthalylsulfathiazole...

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Aeromonas media

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and tetracycline, but not to ampicillin, cloxacillin, novobiocin, or sulfafurazole. It produces a bacteriocin-like inhibitory substance. Allen, D. A.;...

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IARC group 3

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Succinic anhydride Sudan I Sudan II Sudan III Sudan Brown RR Sudan Red 7B Sulfafurazole (Sulfisoxazole) Sulfamethazine Sulfamethoxazole Sulfites Sulfur dioxide...

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Eosinophilic myocarditis

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tetracyclins (e.g. tetracycline), sulfonamides (e.g. sulfadiazine, sulfafurazole), sulfonylureas, antituburcular drugs (e.g. isoniazid, 4-aminosalicylic...

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