American man immune to HIV/AIDS due to a genetic mutation
Stephen Crohn
Born
Stephen Lyon Crohn
(1946-09-05)September 5, 1946
New York City, U.S.
Died
August 23, 2013(2013-08-23) (aged 66)
New York City, U.S.
Occupation
Artist
Stephen Lyon Crohn (September 5, 1946 – August 23, 2013)[1] also known as "The man who can't catch AIDS", was a man notable for a genetic mutation, which caused him to be immune to AIDS. He was a great-nephew of Burrill Bernard Crohn, for whom Crohn's disease is named.[2]
Crohn had the "delta 32" mutation on the CCR5 receptor,[3][4] a protein on the surface of white blood cells that is involved in the immune system and serves as an access route for many forms of HIV virus to enter and infect host cells. This mutation rendered him effectively immune to many forms of HIV.
^John Schwartz (September 14, 2013). "Stephen Crohn, Who Furthered AIDS Study, Dies at 66". The New York Times. Retrieved September 16, 2013.
^"In memoriam: Steve Crohn". Hudson Valley One. 20 September 2013. Retrieved 30 September 2020.
^Tom Wilkie (September 16, 2013). "The man who can't catch AIDS". The Independent. Archived from the original on 2022-05-25. Retrieved September 16, 2013.
^NOVA (PBS airdate: February 2, 1999) (February 2, 1999). "Surviving AIDS". NOVA (PBS). Retrieved September 16, 2013.{{cite web}}: CS1 maint: numeric names: authors list (link)
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