The Sprague effect is the phenomenon where homonymous hemianopia, caused by damage to the visual cortex, gets slightly better when the contralesional superior colliculus is destroyed.[1][2] The effect is named for its discoverer, James Sprague, who observed this phenomenon in 1966 using a cat model.[3] Several reasons have been thought of for this happening, including mutual inhibition between the two brain hemispheres.[4] For similar reasons of inhibiting an inhibitory structure, damaging the substantia nigra, for instance by using ibotenic acid, can also cause the same improvement.[5]
^Weddell, Rodger A. (August 2004). "Subcortical modulation of spatial attention including evidence that the Sprague effect extends to man". Brain and Cognition. 55 (3): 497–506. doi:10.1016/j.bandc.2004.02.075. PMID 15223196.
^Lomber, Stephen G.; Malhotra, Shveta; Sprague, James M. (2007-02-01). "Restoration of Acoustic Orienting Into a Cortically Deaf Hemifield by Reversible Deactivation of the Contralesional Superior Colliculus: The Acoustic "Sprague Effect"". Journal of Neurophysiology. 97 (2). United States: Journal of Applied Physiology: 979–993. doi:10.1152/jn.00767.2006. PMID 17151228.
^Sprague, James M. (1966-09-23). "Interaction of Cortex and Superior Colliculus in Mediation of Visually Guided Behavior in the Cat". Science. 153 (3743): 1544–1547. doi:10.1126/science.153.3743.1544. PMID 5917786.
^Hilgetag, Claus C. (2000-06-01). "Spatial neglect and paradoxical lesion effects in the cat — A model based on midbrain connectivity". Neurocomputing. 32–33. ScienceDirect: 793–799. doi:10.1016/S0925-2312(00)00246-0.
^Wallace, Steven F.; Rosenquist, Alan C.; Sprague, James M. (1990). "Ibotenic acid lesions of the lateral substantia nigra restore visual orientation behavior in the hemianopic cat". The Journal of Comparative Neurology. 296 (2). Wiley-Blackwell: 222–252. doi:10.1002/cne.902960204.
The Spragueeffect is the phenomenon where homonymous hemianopia, caused by damage to the visual cortex, gets slightly better when the contralesional superior...
been shown to improve visual deficits in a phenomenon known as the Spragueeffect. Homonymous hemianopsia can be broken down as follows: Homonymous: (Greek...
due to counterbalancing brain lesions due to a process known as the Spragueeffect. Hemianopia (Hemianopsia) Archived 16 May 2017 at the Wayback Machine...
Sprague Electric Company was an electronic component maker founded by Robert C. Sprague in 1926. Sprague was best known for making a large line of capacitors...
albino Wistar rat, which is still widely used. Other common strains are the Sprague Dawley, Fischer 344, Holtzman albino strains, Long–Evans, and Lister black...
(monolithic IC) chip. Between late 1958 and early 1959, Kurt Lehovec of Sprague Electric Company developed a way to electrically isolate components on...
Gigandet". Screen Anarchy. Retrieved 25 July 2020. Sprague, Mike (24 April 2017). "EXCLUSIVE THE SHADOW EFFECT CLIP W/ MICHAEL BIEHN GOES FULL CLOCKWORK ORANGE"...
Charles A. Sprague High School, known as Sprague High School, is a high school in the Sunnyslope neighborhood of Salem, Oregon, United States. The school...
neighbourhood effect. The first group that attempted to find an empirical link between social interaction and voting patterns was R. Huckfeldt and J. Sprague. They...
Ian Broun Sprague (1920–1994) was an Australian twentieth-century studio potter, ceramic sculptor and graphic artist. Delayed by the Second World War...
film "hypnotically unsettling", giving the film a 4 out of 4 rating. Mike Sprague of JoBlo.com said the film was "just as unsettling and entertaining as...
The Sprague Fire was a wildfire in Glacier National Park in Montana. It was first reported on August 10, 2017, around 8:30 pm after being caused by a...
Amory, Edward Heathcoat : "A fearful symmetry", 6 June 1998, The Spectator Sprague, Jonathan : "Foreigners at the Wheel : A new boss at scandal-hit Mitsubishi...
northernmost of the three escort carrier groups under Rear Admiral Clifton Sprague that comprised the only American forces remaining in the area. Composed...
the original on 8 December 2023. Retrieved 8 December 2023. Lee, K. C.; Sprague, M. R.; Sussman, B. J.; Nunn, J.; et al. (2 December 2011). "Entangling...
announced by Secretary of State Oliver Dowden. Robert C. Sprague 1900-1991 - founder of Sprague Electric company "Vishay Intertechnology, Inc. 2023 Annual...
no non-lethal instruments for exploring internal anatomy. Rappaport and Sprague designed a new stethoscope in the 1940s, which became the standard by which...
while investigating the house of Theodore Sprague, whom she believes to be Sylar. She and Parkman find Sprague in the hospital with his dying wife, but...
butterfly effect and is used as an example of how to consider chaos theory and the physics of time travel. "A Gun for Dinosaur" – Short story by L. Sprague de...
incomes"; similarly, the American economist Oliver Mitchell Wentworth Sprague, in the Economic Journal, argued that "conscription of men should logically...
section's stops and starts were simultaneously precise and brutal. David Sprague suggests that "Yow's disjointed couplets" are reminiscent of a "preacher...
highest dose measured. A sub-chronic 90-day nose-only inhalation study in Sprague–Dawley (SD) rats exposed to 0.03, 0.16 and 0.66 mg/L glycerin (Per liter...