Sp4 transcription factor information

SP4
Identifiers
Aliases	SP4, HF1B, SPR-1, Sp4 transcription factor
External IDs	OMIM: 600540; MGI: 107595; HomoloGene: 2341; GeneCards: SP4; OMA:SP4 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	21,514,822 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	118,265,175 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; germinal epithelium; ; superficial temporal artery; ; retinal pigment epithelium; ; trabecular bone; ; endothelial cell; ; Brodmann area 23; ; biceps brachii; ; right ventricle; ; urethra;
	Top expressed in
	retinal pigment epithelium; ; ciliary body; ; ganglionic eminence; ; medial ganglionic eminence; ; iris; ; barrel cortex; ; thymus; ; cerebellar vermis; ; submandibular gland; ; substantia nigra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleic acid binding; DNA-binding transcription factor activity; DNA binding; transcription coactivator activity; protein binding; metal ion binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cytosol;
Biological process	regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	6671
	20688
	ENSG00000105866
	ENSMUSG00000025323
	Q02446
	Q62445
	NM_003112; NM_001326542; NM_001326543
	NM_001166385; NM_009239
	NP_001313471; NP_001313472; NP_003103
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor Sp4 is a protein that in humans is encoded by the SP4 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105866 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025323 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hagen G, Müller S, Beato M, Suske G (November 1992). "Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes". Nucleic Acids Research. 20 (21): 5519–25. doi:10.1093/nar/20.21.5519. PMC 334381. PMID 1454515.
^ "Entrez Gene: SP4 Sp4 transcription factor".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105866 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025323 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1454515-5] Hagen G, Müller S, Beato M, Suske G (November 1992). "Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes". Nucleic Acids Research. 20 (21): 5519–25. doi:10.1093/nar/20.21.5519. PMC 334381. PMID 1454515.

[entrez-6] "Entrez Gene: SP4 Sp4 transcription factor".

Sp4 transcription factor information

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