South Dakota Highway 46 is a 105.535-mile (169.842 km) state highway in South Dakota, United States, that runs west to east across the southeastern part of the state. It begins at the junction of U.S. Highway 18 and U.S. Highway 281 in Pickstown, and runs due east to nearly the Iowa border, before curving south to cross the border and meeting Iowa Highway 10.
^"State Highway Log" (PDF). Mitchell region: South Dakota Department of Transportation. January 2011. pp. 117–123. Retrieved December 23, 2011.
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