US 1 / US 25 / US 78 / US 278 / SR 10 / SR 121 at the GA state line near North Augusta
Major intersections
I-20 in North Augusta
US 178 / SC 39 in Saluda
US 378 in Saluda
US 76 in Newberry
I-26 in Newberry
US 176 near Whitmire
US 321 / SC 9 in Chester
North end
US 21 / SC 322 in Rock Hill
Location
Country
United States
State
South Carolina
Counties
Aiken, Edgefield, Saluda, Newberry, Union, Chester, York
Highway system
South Carolina State Highway System
Interstate
US
State
Scenic
← SC 120
→ SC 122
South Carolina Highway 121 (SC 121) is a 134.200-mile (215.974 km) major state highway that travels north and south in central parts of the U.S. state of South Carolina. The highway is actually part of a long multi-state highway that also exists in Florida and Georgia, as Florida State Road 121 and Georgia State Route 121, respectively.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved December 4, 2020.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved December 4, 2020.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved December 4, 2020.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved December 4, 2020.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved December 4, 2020.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved December 4, 2020.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved December 4, 2020.
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Global Information
US 1 / US 25 / US 78 / US 278 / SR 10 / SR 121 at the GA state line near North Augusta
US 21 / SC 322 in Rock Hill
