Protein-coding gene in the species Homo sapiens
STX1B Identifiers Aliases STX1B , STX1B1, STX1B2, GEFSP9, syntaxin 1BExternal IDs OMIM: 601485; MGI: 1930705; HomoloGene: 69375; GeneCards: STX1B; OMA:STX1B - orthologs Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p11.2 Start 30,989,256 bp[1] End 31,010,638 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 127,403,072 bp[2] End 127,423,721 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right frontal lobe Brodmann area 9 prefrontal cortex cingulate gyrus anterior cingulate cortex postcentral gyrus superior frontal gyrus nucleus accumbens hypothalamus
Top expressed in superior frontal gyrus cerebellar cortex dentate gyrus of hippocampal formation granule cell pontine nuclei dorsal tegmental nucleus dorsomedial hypothalamic nucleus cerebellar vermis medial vestibular nucleus lobe of cerebellum subiculum
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
SNAP receptor activity
protein kinase binding
signaling receptor binding
SNARE binding
protein domain specific binding
Cellular component
integral component of membrane
cytosol
membrane
synaptic vesicle
plasma membrane
spindle
microtubule organizing center
SNARE complex
cytoskeleton
nuclear lamina
nucleus
nucleoplasm
centrosome
cytoplasm
presynaptic membrane
presynapse
presynaptic active zone membrane
axon
neuromuscular junction
endomembrane system
Biological process
synaptic vesicle docking
spontaneous neurotransmitter secretion
positive regulation of neurotransmitter secretion
regulation of exocytosis
vesicle docking
positive regulation of excitatory postsynaptic potential
regulation of gene expression
protein transport
intracellular protein transport
neurotransmitter transport
vesicle-mediated transport
regulation of synaptic vesicle priming
negative regulation of neuron projection development
regulation of synaptic activity
vesicle docking involved in exocytosis
calcium ion-regulated exocytosis of neurotransmitter
protein localization to membrane
negative regulation of synaptic vesicle recycling
positive regulation of spontaneous neurotransmitter secretion
negative regulation of macropinocytosis
synaptic vesicle fusion to presynaptic active zone membrane
exocytic insertion of neurotransmitter receptor to postsynaptic membrane
synaptic vesicle exocytosis
exocytosis
vesicle fusion
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 16: 30.99 – 31.01 Mb Chr 7: 127.4 – 127.42 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Syntaxin-1B is a protein that in humans is encoded by the STX1B gene.[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000099365 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030806 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Entrez Gene: STX1B2 syntaxin 1B2".
Last Update: 2022-10-28T16:25:36Z
Syntaxin-1B is a protein that in humans is encoded by the STX1B gene. STX1B has been shown to interact with UNC13B. GRCh38: Ensembl release 89: ENSG00000099365...
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Last Update: 2022-06-30T00:15:43Z
Syntaxin 1 (STX1B ) which lacks the transmembrane domain localizes in the nuclei. Human genes encoding syntaxin proteins include: STX1A, STX1B , STX2, STX3...
Word Count : 682
Last Update: 2023-12-27T04:31:36Z
Q-SNARE SNAP25 SNAP29 Syntaxin STX1A STX1B STX2 STX3 STX4 STX5 STX6 STX7 STX8 STX10 STX11 STX12 STX16 STX17 STX18 STX19 Munc-18: STXBP1 STXBP2 STXBP3...
Word Count : 6538
Last Update: 2024-03-22T09:50:54Z
February 8, 2021. Cassandra L. Kniffin (January 8, 2015). "SYNTAXIN 1B; STX1B ". Online Mendelian Inheritance in Man (OMIM). National Library of Medicine...
Word Count : 1233
Last Update: 2023-12-03T18:44:33Z
UNC13B has been shown to interact with: DOC2A, RIMS1, SPTBN2, STX1A, and STX1B . GRCh38: Ensembl release 89: ENSG00000198722 – Ensembl, May 2017 GRCm38:...
Word Count : 1188