SH2D2A information

SH2D2A
Identifiers
Aliases	SH2D2A, F2771, SCAP, TSAD, VRAP, SH2 domain containing 2A
External IDs	OMIM: 604514 MGI: 1351596 HomoloGene: 2958 GeneCards: SH2D2A
Gene location (Human)
Chr.	Chromosome 1 (human)
End	156,816,848 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	87,763,029 bp
RNA expression pattern
	Top expressed in
	blood; ; spleen; ; appendix; ; lymph node; ; upper lobe of left lung; ; gallbladder; ; right lung; ; bone marrow cells; ; thymus; ; left uterine tube;
	Top expressed in
	thymus; ; blood; ; spleen; ; subcutaneous adipose tissue; ; jejunum; ; islet of Langerhans; ; ileum; ; heart; ; placenta; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding; protein binding;
Cellular component	cytoplasm; cytosol;
Biological process	multicellular organism development; cell differentiation; vascular endothelial growth factor receptor signaling pathway; cell population proliferation; angiogenesis; signal transduction; positive regulation of signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	9047
	27371
	ENSG00000027869
	ENSMUSG00000028071
	Q9NP31
	Q9QXK9
	NM_001161441; NM_001161442; NM_001161443; NM_001161444; NM_003975
	NM_001025571; NM_021309
	NP_001154913; NP_001154914; NP_001154915; NP_001154916; NP_003966
	NP_001020742; NP_067284
	Wikidata
View/Edit Human	View/Edit Mouse

SH2 domain-containing protein 2A is a protein that in humans is encoded by the SH2D2A gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000027869 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028071 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Spurkland A, Brinchmann JE, Markussen G, Pedeutour F, Munthe E, Lea T, Vartdal F, Aasheim HC (February 1998). "Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites". The Journal of Biological Chemistry. 273 (8): 4539–46. doi:10.1074/jbc.273.8.4539. PMID 9468509.
^ "Entrez Gene: SH2D2A SH2 domain protein 2A".

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